4-(2'-(N-(1-메틸-3-(3'-카바밀페닐)-n-프로필))아미노에틸)-1-히드록시-2- 피리돈의 합성

Synthesis of 4-(2'-(N-(1-methyl-3'-carbamylphenyl)-n-propyl))aminoethyl)-1-hydroxy-2-pyridone

The 4-(2'-(N-(l-methyl-3'-carbamylphenyl)-n-propyl))aminoethyl)-l- hydroxy-2-pyridone which has isoelectronic and isosteric structural similarity with dobutamine without having the Catechol-O- Methyltransferase(COMT) vulnerable m-hydroxy group was synthesized via 12 synthetic steps.