Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Inhibitory Effects of Chinese Pepper on the Mutagenicity and the Growth of MG-63 Humman Osteosarcoma Cells

초피 추출물의 항돌연변이 및 MG-63 암세포 증식억제 효과ㅤ

  • 김소희 (동주여자전문대학 식품영양학과) ;
  • 박건영 (부산대학교 식품영양학과)
  • Published : 1993.12.01
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Abstract

The inhibitory effects of various extracts from Chinese pepper on the mutagenicity and the growth of MG-63 human osteosarcoma cells were studied. Chinese pepper was extracted with methanol and then the methanol extract was further fractionated by using hexane, chloroform, ethyl acetate and butanol. The methanol extract of Chinese pepper revealed the strong antimutagenic activity on the aflatoxin B1(AFB1) and N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) in Ames mutagenicity test and SOS chromotest.

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