Analytical Science and Technology (분석과학)
- Volume 6 Issue 1
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- Pages.21-27
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- 1993
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- 1225-0163(pISSN)
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- 2288-8985(eISSN)
A Study on the Separation of n-Hexane by Molecular Sieve 5A and the Purification for HPLC use
분자체 5A를 이용한 n-헥산의 분리와 HPLC급으로의 정제에 관한 연구
- Choi, Beom Suk (Department of Chemistry, KyungHee University) ;
- Kim, Young Man (Advanced Analysis Center, KIST) ;
- Kim, Sun Tae (Advanced Analysis Center, KIST)
- Received : 1993.01.08
- Published : 1993.03.25
Abstract
Technical grade n-hexane whose purity is 54% has been purified for HPLC use. Methylcyclopentane, 2-methylpentane, and 3-methylpentane which are hardly isolated by fractional distillation were separated by the liquid-solid chromatography using molecular sieve 5A. UV and fluorescence impurities whose contents are critically regulated for HPLC solvent were removed by the adsorptive separation with alumina and silica gel. The present method also reduced the impurities of color(APHA), acidity, water, residue after evaporation, sulfur, and thiophene content, and the impurity contents were well within the specifications of HPLC solvent.
54% 순도의 공업용 n-헥산을 HPLC급으로 분리, 정제하였다. 분별증류법으로 분리하기 어려운 methylcyclopentane, 2-methylpentane, 그리고 3-methylpentane 등은 molecular aieve 5A를 이용한 액체-고체 크로마토그래피법으로 분리하였다. HPLC 용매로서 엄격히 규제받는 UV와 형광불순물은 알루미나와 실리카겔을 이용한 흡착법으로 정제하였다. 이와 같은 방법으로 n-헥산을 정제함으로써 수분, 색도(APHA), 산도, 증발잔류물, 황 및 thiophene 등의 불순물 항목을 모두 HPLC급의 규격까지 낮출 수 있었다.