Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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A Cross-sectional Study on the Risk Factors Related to Fatty Liver

지방간의 위험요인에 관한 단면적 연구

  • Ohm, S.H. (Department of Preventive Medicine, Inje University, College of Medicine) ;
  • Yoo, B.C. (Department of Preventive Medicine, Inje University, College of Medicine) ;
  • Kim, S.J. (Department of Preventive Medicine, Inje University, College of Medicine) ;
  • Lee, C.U. (Department of Preventive Medicine, Inje University, College of Medicine) ;
  • Pai, K.T. (Department of Preventive Medicine, Inje University, College of Medicine) ;
  • Kim, S.C. (Department of Preventive Medicine, Inje University, College of Medicine) ;
  • Shin, H.R. (Department of Preventive Medicine, Inje University, College of Medicine)
  • 엄상화 (인제대학교 의과대학 예방의학교실) ;
  • 유병철 (인제대학교 의과대학 예방의학교실) ;
  • 김성준 (인제대학교 의과대학 예방의학교실) ;
  • 이채언 (인제대학교 의과대학 예방의학교실) ;
  • 배기택 (인제대학교 의과대학 예방의학교실) ;
  • 김성천 (인제대학교 의과대학 예방의학교실) ;
  • 신해림 (인제대학교 의과대학 예방의학교실)
  • Published : 1993.06.01
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Abstract

Generally fatty liver is attributed either to chronic alcoholism, diabetes mellitus, or obesity. Based upon this commonly held clinical brief, this study was conducted to investigate the contributing factors of fatty liver and odds ratio (OR) of known contributing factors. A sample of 310 male participants, who visited at Seoul Paik Automated Multiphasic Health Testing System from November 1991 to December 1991, was separated into 112 cases and 198 controls by ultrasonographic fin ding. There were statistically significant difference between fatty liver and normal in triglyceride (TG), body mass index (BMI), alanine aminotransferase (ALT), high density lipoprotein cholesterol (HDL-C), fasting blood sugar (FBS), alcohol consumption, low density lipoprotein cholesterol (LDL-C), total cholesterol, gamma-glutamyl transferase ($\gamma$-GT), duration of alcohol intake and alkaline phosphatase (Alk.P)(P<0.01, P<0.05). The statistically significant elevated odds ratio were noted for TG (4.48, confidence interval (CI) 2.66-7.55, P=0.000), alcohol consumption(3.24, CI 1.56-6.23, P=0.002), BMI(3.05, CI 1.87-4.97, P=0.000), and FBS (2.59, CI 1.53-4.40, P=0,000). In summary, it is suggested that the fatty liver could be preventive by avoiding such deleterious factors as high fat diet, alcohol and obesity.

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