Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Identification of insecticidal compounds from Streptomyces sp. no. 46

Streptomyces sp.no. 46이 생산하는 살충성 물질의 구조 동정

  • Oh, Sei-Ryang (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology) ;
  • Lee, Hyeong-Kyu (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology) ;
  • Koo, Bon-Tak (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology) ;
  • Choi, Soo-Keun (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology) ;
  • Park, Sang-Gu (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology) ;
  • Shin, Byung-Sik (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology) ;
  • Park, Seung-Hwan (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology) ;
  • Kim, Jeong-Il (Applied Microbiology Research Group, Genetic Engineering Research Institute, Korea Institute of Science and Technology)
  • 오세량 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 이형규 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 구본탁 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 최수근 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 박상구 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 신병식 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 박승환 (KIST 유전공학연구소 응용미생물 연구그룹) ;
  • 김정일 (KIST 유전공학연구소 응용미생물 연구그룹)
  • Published : 1994.04.30
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Abstract

In searching for new insecticidal compounds from soil microorganisms, strains of streptomyces species showed insecticidal activities on Musca domestica and Bombyx mori were selected. Compounds I-IV, which were isolated from the metabolites of no. 46 strain, were identified as piericidin $C_1$, $C_2$, $C_3$ and $D_1$, respectively by UV and NMR data analyses.

토양에서 분리된 방선균에서 생산되는 살충성 물질을 스크리닝하는 연구과정중 선발된 no. 46균주가 생산하는 살충성 물질을 분리하였다. 분리된 물질 4가지는 UV, $^1H-NMR$, $^{13}C-NMR$, C-H COSY 방법으로 구조 분석한 결과, Piericidin $C_1$, $C_2$, $C_3$ 그리고 $D_1$으로 각각 동정되었다.

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