Archives of Pharmacal Research
- Volume 17 Issue 3
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- Pages.170-174
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- 1994
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis and Biological Activity of 6-Substituted-2-Oxo-Purine Nucleosides
- Lee, Sang-Jun (Department of Food and Biotechnologyand & Bioproducts Research Center, Yonsei University) ;
- Kim, Jong-Bae (Animal Resource Research Center, Kun Kuk University) ;
- Cho, Young-Ho (Animal Resource Research Center, Kun Kuk University) ;
- Kim, Jung-Han (Department of Food and Biotechnologyand Bioproducts Research Center, Yonsei University)
- Published : 1994.06.01
Abstract
We have synthesized various 6-substituted 2-oxo-purine nucleosides from key intemediate, 6-[(4-methylphenylthio)-2-oxo-9(2, 3, 5tri-o-acetyl-
Keywords
- 6-Substituted-2-oxo-purine nucleosides;
- Nucleophilic subtitution;
- lsoguanosine analogs 6-[(4-methylphenythio)-2-oxo-9-(2,3,5,-tri-o-actyl-${\beta}$-D-ribofuranosyl]-2,3-dihydropurnie;
- Nucleophilic substitution