Effects of Feeding the Mixture of Lineseed and Sunflower Seed Oil on the Lipid Components and Fatty Acid Compositions of Liver in Dietary Hyperlipidemic Rats

아마인유와 해바라기 종자유의 혼합급이가 식이성 고지혈증 흰쥐의 간장 지질성분 및 지방산 조성에 미치는 영향

  • 최운정 (서강전문대학 식품영양과) ;
  • 김한수 (경상대학교 식품영양학과) ;
  • 김성희 (경상대학교 식품영양학) ;
  • 이호신 (경상대학교 식품영양학과) ;
  • 서인숙 (경상대학교 식품영양학과) ;
  • 정승용 (경상대학교 식품영양학과)
  • Published : 1994.04.01

Abstract

This study was carried out to investigate the effect of the feeding mixture of linesed oil, rich in n-3 PUFA and the sunflower seed oil, rich in n-6 PUFA on the lipid metabolism in the dietary hypprlidemic rats. After male Sprague-Dawley rats were induced hyperlipidemia by feeding the diet containing lard, butter, and cholesterol for 3 weeks, then they were fed with the diet containing lard 3.0% and butter 12.0% for control, the mixture in different proportion of both linseed oil and sunflower seed oil, and antihyperlipidemic durgs for 2 weeks. Analysis of the lipid component and the fatty acid composition of the liver showed following results. Concentration s of the total cholesterol and phospholipid in liver were significantly higher in group 2 (olive oil 12.0%) and lower in the other groups than in the control group, especially lower in groups 3 (cholestyramine 2.0%) and 9 (sunflower seed oil 12.0%) . Concentration of triglyceride was lower in the other groups except group 4 (liparoid), especially lowe rin group 9 than in the control group. In the fatty acid composition of liver lipids, C18:2 was the major fatty acid. Contents of n-6 PUFA increased , while those of n-3 PUFA decreased in groups composition of the test lipids. From the data on concentration s of total cholesterol. Phospholipid and triglyceride in liver, we concluded that the feeding mixed with 3.0% lard and 12.0 % sunflower seed oil were most effective for the improvement of the live lipids. The fatty acid composition in liver lipids were affected by the fatty acid composition of the test lipids.

Keywords

References

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