Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Alleviating Effects of Vitamin C on the Gramoxone Toxicity in the Mucosubstances of Rat Duodenum

흰쥐 십이지장 점액질에 미치는 Gramoxone 독성에 대한 비타민 C의 완화 효과

  • Jo, Un-Bock (Dept . of Biology Education , Pusan National University) ;
  • Kim, Sung-Ro (Dept. of Food and Nutrition , Dongnae Women's Junior College) ;
  • Park, Byung-Tae (Dept . of Biology Education , Pusan National University)
  • Published : 1994.06.01
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Abstract

The effect of vitamin C on th egramoxone toxicity in the duodenal globlet cells of rats were investigated suing histochemical methods. Rats in control, gramoxone and gramoxone+vitmain C (Vt.C) group, aged 6 to 7 weeks, were fed 18% casein diet. In th egramoxone group, neutral and acid mucins of the globlet cells in villi and crypts of duodenum tended to decrease as compared with the control group. And the globle cells secreting nonsuphated mucins tended to increase in number, being usually accompanied by a decrease of the globlet cells secreting suphated mucins which are prominent in the duodenal mucosa of control group. However, the goblet cells secreting nonsuphated mucins tended to increase in the gramoxone + Vt.C group. Morphological changes of the globlet cells in the gramoxone group were noted vacuolation and demolition of globlet cells, while those changes were not significant in the gramoxone +Vt. C group. It seems to be that Vt. C has alleviating effects on the gramoxone toxicity in secretion and production of the duodenal goblet cells.

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References

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