Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effects of Sodium Alginate and Cellulose on Fasting Plasma Lipoprotein Composition and Choelsterol Metabolism in Rats (I)

Sodium Alginate와 Cellulose 가 흰쥐의 공복 혈장 Lipoportein 조성과 콜레스테롤 대사에 미치는 영향 (I)

  • 강희정 (부산대학교 식품영양학과) ;
  • 서명자 (부산대학교 식품영양학과) ;
  • 김은희 (부산대학교 식품영양학과) ;
  • 송영선 (인제대학교 식품영양학과)
  • Published : 1994.12.01
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Abstract

This study was carried out to determine, the effects of sodium alginate and cellulose on the plasma lipoportein composition and cholesterol metabolism inrats.Each experimental diet contained 105 sodium alginate and cellulose by weight, respectivley and rats were fed fro 4 weeks. The results obtained were as follows : The feeding of sodium alginate and cellulose decreased total plasma cholesterol slightly . total cholesterol of Chylomicron /VLDL- , LDL-fraction and liver were decreased significantly insodium alginate group. HDL-cholesterol was slightly increased in soidum alginate group. The feeding of sodium alginate significantly lowered plasma , Chylomicron VLDL-, LDL-fraction and liver TG concentrations compared with those fed fiber-free diet . The HMG-CoA reductase activity was not different among diet groups but the lowest activity was observed in sodium alginate group. The feeding of sodium alginate significantly increased fecal cholesterol , TG, and bile acid excretion . In summary , the ingestion of sodium alginate decreased cholesterol and TG concentrations of plasma and liver. This may be explained by the facts that fecal cholesterol, bile acid and TG level were increased significantly in sodium alginate group.

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