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TRANSGENIC LIVESTOCK - Review -

  • Jin, D.I. (Department of Microbiology and Immunology, Duke University Medical Center) ;
  • Petters, R.M. (Reproductive Physiology Research Laboratory, Department of Animal Science, North Carolina State University) ;
  • Im, K.S. (Department of Animal Science and Technology, Collage of Agriculture and Life Sciences, Seoul National University)
  • Received : 1993.03.15
  • Accepted : 1993.09.04
  • Published : 1994.03.01

Abstract

There are several gene transfer methods available to introduce foreign DNA into animal. The most common method at present is microinjection. However, the overall efficiency of producing practical application of gene transfer technology to livestock species is production of pharmaceuticals. Rare human proteins, which cannot be produced into milk of transgenic animals. Large amount of biologically active protein may be obtained from transgenic farm animals using this system. Growth-related application to livestock species using growth hormone genes or factor genes have been disappointing. There were many undesirable side effects noted in the transgenic animals. More sophisticated on or off transgene expression are needed to control expression of transgenes in the transgenic animals. Turning positive effects while circumventing potentially harmful effects.

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