AN EXPERIMENTAL STUDY ON THE CYTOTOXICITY OF VARIOUS ORTHODONTIC BANDS

수종 교정용 Band의 세포독성에 관한 실험적 연구

  • Yoo, Dong-Hwan (Department of Orthodontics, College of Dentistry, Wonkwang University) ;
  • Kook, Yoon-Ah (Department of Orthodontics, College of Dentistry, Wonkwang University) ;
  • Kim, Sang-Cheol (Department of Orthodontics, College of Dentistry, Wonkwang University)
  • 유동환 (원광대학교 치과대학 교정학교실) ;
  • 국윤아 (원광대학교 치과대학 교정학교실) ;
  • 김상철 (원광대학교 치과대학 교정학교실)
  • Received : 1994.04.01
  • Published : 1994.06.30

Abstract

The purpose of this study was to investigate the cytotoxicity of orthodontic bands in vitro and in vivo4 types of orthodontic bands were applied to cultured fibroblast and the supernatants were injected into dorsal subcutaneous tissue of mice. In vitro.the cytotoxixity was evaluated by an MTT assay after 2 and 6days. In vivo, the histopathologic observation was performed 2 days after injection. The results were : 1. The cell viability was significantly decreased in the group added phosphoric acid in comparison to control group, but there was not any significance among the experimental group after 2 days. 2. Cell viability decreased in the high Ni containing group after 6 days. 3. The histopathological finding was that the Cr-containing group showed severe infiltration of inflammatory cells and muscular destruction.

Keywords