Korean Journal of Food Science and Technology (한국식품과학회지)

Korean Society of Food Science and Technology (한국식품과학회)
권호 표지

Screening for Antimutagenic Compounds in Unused Marine Resources by the Modified Ames Test

수산 미이용자원 중에 존재하는 항변이원성 물질의 검색

  • Cho, Soon-Yeong (Department of Food Science, Kangnung National University) ;
  • You, Byeong-Jin (Department of Food Science, Kangnung National University) ;
  • Chang, Mi-Hwa (Department of Food Science, Kangnung National University) ;
  • Lee, Soo-Jung (Department of Food and Nutrition, Gyeongsang National University) ;
  • Sung, Nak-Ju (Department of Food and Nutrition, Gyeongsang National University)
  • Published : 1995.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

To detect naturally occurring antimutagenic substances from unused marine resources, the screening for the antimutagenic compounds containing in various solvent extracts of eight unused marine resources by modified Ames test was carried out. The tested unused marine resources were Asterina pectinifera, Halocynthia roretzi skin, Nototodarus sloani ink, Anthocidaris crassispina skin, Sargassum horneri, Agarum cribrosum, Odonthalia corymbifera and Desmarestia ligulata. The ether extracts of Halocynthia roretzi skin showed the only antimutagenic effect among several solvent extracts of tested samples. The effect increased with increasing concentration of the ether extracted ones.

천연 생리활성물질의 개발과 수산미이용자원의 효율적 이용방안을 모색하기 위하여 별불가사리, 오징어먹즙, 성게껍질, 우렁쉥이 껍질, 구멍쇠미역, 산말, 모자반, 참빗풀 등을 대상으로 물, 에테르, 아세톤, 메탄올로 순차 용매추출하여 각 시료의 각 용매 추출구간별로 항변이 원성 물질 검색을 시도하였다. 항변이원성 검색 결과, 8종의 수산 미이용자원의 여러 순차 용매 추출구들 중에서도 단지 우렁쉥이 껍질의 에테르 추출구에서만 변이원 활성 억제효과가 나타났으며, 그 추출액의 농도가 높을수록 항변이원성 효과가 증가하는 경향을 보였다.

Keywords