Purification of Antimicrobial Substance for the Extract from the Root Bark of Morus alba

상백피 추출물로부터 향균성 물질의 분리정제

  • 박욱연 (부산수산대학교 식품공학과) ;
  • 김신희 (부산수산대학교 식품공학과) ;
  • 김지회 (국립수산진흥원 이용가공실) ;
  • 김용관 (부산전문대학 식품가공과) ;
  • 장동석 (부산수산대학교 식품공학과)
  • Published : 1995.12.01


The ethanol extract from the root bark of Morus alba showed the strongest antimicrobial activity on the growth of almost all the tested microorganisms which were food-borne pathogens and food-related microorganisms. 1) In order to isolate and purify of antimicrobial substance extracted from the root bark of Morus alba, the antimicrobial substance from the ethanol extract which exhibited a strong antimicrobial activity was purified by solvent fractionation, silica gel column chromatography, TLC and HPLC. Among the fractions fractionated by 4 kind of solvents from the ethanol extract, the antimicrobial activity of ethyl acetate fraction had the strongest antimicrobial activity against B. subtilis. Unknown compound were isolated from the ethyl acetate fraction by silica gel column chromatography, TLC and HPLC and the compounds showed strong absorbance at 207, 217 and 285 nm, therefore, it was supposed to be a kinds of aromatic compound.