Effect of Calcium Intake on Calcium, Sodium and Potassium Metabolism in Young and Adult Female Rats

칼슘의 섭취수준이 연령이 다른 암쥐의 칼슘, 나트륨 및 칼륨대사에 미치는 영향

  • 승정자 (숙명여자대학교 가정대학 식품영양학과)
  • Published : 1995.05.01

Abstract

The purpose of this research was to investigate the effect of calcium levels(50, 100 and 200% of requirement) on metabolism of Ca, Na and K in Young and adult female rats for 3 weeks. There was no significant difference in feed intake, body weight gain and feed efficiency ratio among the groups of different Ca intake level. Serum Na level of high-Ca group was significantly lower than that of low-Ca or normal-Ca group in Young rats. There was no significant difference in liver Ca and K contents among the groups of different Ca intake levels. But, Na content in liver was decreased by the increase of dietary Ca intake. Ca content in kidney of high-Ca group in young rats and normal-Ca group in adult rats were significantly higher than those of other groups. Na content in kidney of low-Ca group was lower than those of normal-Ca and high-Ca groups. Urinary excretions of Na and K and fecal excretion of Ca were increased by the increase of dietary Ca intake. But, fecal excretions of Na and K were not affected by dietary Ca intake. According to this study, it was found that the high Ca consumption promotes excretions of fecal Ca and urinary Na and K in rats. The study verifies the need for more study on the interrelationship among Ca, Na and K metabolism and bood pressure.

Keywords

References

  1. Miner Electrolyte Metab v.16 Effect of age on calcium and phosphate absorption Armbrecht,H.J.
  2. Am J Clin Nutr v.55 Calcium balance during human growth : Evidence for threshold behavior Matkovic,V.;Heaney,R.P.
  3. J Nutr v.108 Effect of phosphorus on the absorption of calcium and on the calcium balance in man Spencer,H.;Kramer,L.;Osis,D.;Norris,C.
  4. Am J Clin Nutr v.36 Vitamin D and bone health in the elderly Prafitt,A.M.;Gallagher,J.C.;Heaney,R.P.;Johnston,C.C.;Neer,R.;Whedon,G.D.
  5. J Nutr v.109 Bioavailability to rats of zinc, magnesium and calcium in casein-, egg- and soyprotein-containing diets Forbes,R.M.;Weingartner,K.E.;Parker,H.M.;Bell,R.M.;Erdman,J.W.
  6. NZ Med J v.96 Effects of varying dietary salt intake on the fasting urinary excretion of sodium, calcium, and hydroxyproline in young women Goulding,A.
  7. Lancet v.1 Calcium binding by dietary fiber James,W.P.T.;Branch,W.J.;Southgate,D.A.T.
  8. J Nutr v.116 NIH consensus conferance : osteoporosis. Factors contributing to osteoporosis Spencer,H.;Kramer,L.
  9. J Nutr v.116 Influence of injected caffeine on the metabolism of calcium and the retention and excretion of sodium, potassium, phosphorus, magnesium, zinc and copper in rats Yeh,J.K.;Aloia,J.F.;Semla,H.M.;Chen,S.Y.
  10. Am J Physiol v.215 Role of serum Ca, parathyroid hormone, and NaCl infusion on renal Ca and Na clearances Massay,S.B.;Coburn,J.W.;Champman,L.W.;Kleeman,C.R.
  11. Clin Sci v.37 The interrelationships of calcium and sodium excretion Wills,M.R.;Gill,J.R.;Bartter,F.C.
  12. 한국영양학회지 v.20 no.4 한국 성인 여자에 있어서 나트륨섭취수준이 체내 칼슘대사에 미치는 영향 김양애;승정자
  13. Am J Physiol v.200 no.5 Calcium clearances as a function of sodium clearances in the dog Wasler,M.
  14. Ann Rev Nutr v.4 Calcium and osteoporosis Avioli,L.V.
  15. Nutrition, aging and health Calcium intake, bone health, and aging Heaney,R.P.;Young,E.A.(ed.)
  16. J Bone Min Res v.5 no.11 Influence of calcium load on absorption fraction Heaneys,R.P.;Weaver,C.M.;Firzsimmons,M.L.
  17. Nephron v.45 Calcium diet supplementation increases urinary excretion in essential hypertention Lasaridis,A.N.;Sofos,A.B.
  18. N Engl J Med v.310 Correlation of platelet calcium with blood pressure : Effect of antihypertensive therapy Erne,P.;Bolli,P.;Burgisser,E.
  19. J Nutr v.123 The nature and significance of the relationship between urinary sodium and urinary calcium in women Nordin,B.E.C,;Need,A.G.;Morris,H.A.;Horowitz,M.
  20. Renal and electro-acitivity disorders Disorders of calcium, phosphorous, vitamin D and parathyroid hormone activity Popovtzer,M.M.;Schrie,R.W.(ed.)
  21. Metabolism v.28 no.12 Increased dietary calcium lowers blood pressure in the spontaneously hypertensive rat Ayachi,S.
  22. Am J Clin Nutr v.41 The effect of dietary sodium on urinary calcium and potassium excretion in normotensive men with different calcium intakes Castenmiller,J.J.M.;Mensink,R.P.;van der Heijden,L.;Kouwenhoven,T.;Hautvast,J.G.A.J.;de Leeuw,P.W.;Schaafsma,G.
  23. '92 국민영양조사 결과보고서 보건사회부
  24. 한국영양학회지 v.23 no.4 서울지역 성인의 영양보충제 복용실태 이상선;김미경;이은경
  25. 한국영양학회지 v.27 no.3 중년기의 비타민, 무기질 보충제 복용실태 조사 김선효
  26. Nat Aca Sci Nutrient requirements of the laboratory rat NRC Food and Nutrition Board
  27. J Nutr v.107 Report of the American institute of nutrition ad hoc aommittee on standards for nutritional studies American Institute of Nutrition
  28. 식품과 영양 v.7 no.1 식품의 무기성분 분석 임정남
  29. Principles procedures of statistics Steel,R.G.D.;Torrie,J.H.
  30. 한국영양학회지 v.21 no.5 식이내 Ca 수준과 지방 종류를 달리하였을 때 흰쥐의 체내 지방대사에 미치는 영향 권오란;김미경
  31. 한국영양학회지 v.26 no.2 Phytate와 저 Ca 섭취가 흰쥐의 성장기간 동안 Ca, P, An 대사에 미치는 영향 이종호;문수재;허갑범
  32. J Nutr v.92 Effects of dietary calcium upon lipid metabolism in rats fed saturated or unsaturated fat Yacowitz,H.;Fleischman,A.I.;Amsden,R.T.;Bierenbaum,M.L.
  33. J Nutr v.104 Effect of varying dietary level of calcium on plasma and tissue lipids of rabbits Iacono,J.M.
  34. J Nutr v.109 Effects of dietary calcium on blood and tissue lipids, tissue phospholipids, calcium and magnesium levels in rabbits fed diet containing beef tallow Dougherty,R.M.;Iacono,J.M.
  35. J Nutr v.97 Role of calcium in the nutritional etiology of a metabolic disorder in ruminants fed a high grain ration Vipperman,P.E.;Preston,R.L.;Kintner,L.D.;Pfander,W.H.
  36. J Nutr v.120 Influence of dietary calcium and cholecalciferol on composition of plasma lipids in young pigs Foley,M.K.;Galloway,S.T.;Luhman,C.M.;Faidley,T.D.;Beitz,D.C.
  37. Calcium in human biology Nordin,B.E.C.
  38. J Nutr v.92 Effects of dietary calcium upon lipid metabolism in rats fed saturated or unsaturated fat Yacowitz,H.;Fleischman,A.I.;Amsden,R.T.;Bierenbaum,M.L.
  39. Am J Clin Nutr v.52 Effects of moderate caffeine intake on the calcium economy of premenopausal women Barger-Lux,M.J.;Heaney,R.P.;Stegman,M.R.
  40. 한국영양식량학회지 v.23 no.1 단백질과 카페인의 섭취수준이 나이가 다른 흰쥐의 칼슘, 인 나트륨 및 칼륨 대사에 미치는 영향 여정숙;승정자
  41. J Nutr v.104 Relationship of calcium to reproductive abnormalities in the laying hen Roland,D.A.;Sloan,D.R.;Wilson,H.R.;Harms,R.H.
  42. J Nutr v.102 Effect of quantity of dietary calcium on maintenance of bone integrity in mature white leghorn male chickens Norris,L.C.;Kratzer,F.H.;Lin,H.J.;Hellewell,A.B.;Beljan,J.R.
  43. Int J Vitam Nutr Res v.46 Hypocalcemic development in high and low calcium-adapted chicks during acute calcium deficiency Thornton,P.A.
  44. J Am Diet Assoc v.92 Effects of dietary calcium from dairy products on ambulatory blood pressure in hypertensive men Kynast-Gales,S.;Massey,L.
  45. Am J Clin Nutr v.53 Dietary calcium and iron : Effects on blood pressure and hematocrit in young spontaneously hypertensive rats Hatton,D.;Muntzel,M.;Absalon,J.;Lashley,D.;McCarron,D.
  46. J Nutr v.107 Role of dietary calcium and calcium binding protein in cadmium toxicity in rats Washko,P.W.;Cousins,R.J.
  47. J Appl Physiol v.37 Changes in body temperature and blood pressure in rats with calcium and magnesium deficiencies Itokawa,Y.;Tanaka,C.;Fujiwara,M.
  48. J Lab Clin Med v.76 no.6 Experimental enhancement of lead toxicity by low dietary calcium Six,K.M.;Goyer,R.A.
  49. J Nutr v.118 Influence of dietary Ca : P ratio on mineral excretion and nephrocalcinosis in female rats Haek,A.C.;Lemmens,A.G.;Mullink,J.W.M.A.;Beynen,A.C.
  50. J Nutr v.121 Influence of age and magnesium on calcium metabolism in rats McElroy,S.T.;Link,J.E.;Dowdy,R.P.;Zinn,K.R.;Ellersieck,M.R.
  51. 한국영양학회지 v.25 no.7 나이가 다른 단계에서 식이단백질 수준이 흰쥐의 Ca 대사에 미치는 영향 이정아;장영애;김화영
  52. Fed Proc v.43 Short and long-term oral calcium alters blood pressure in essential hypertention Resnick,L.M.;Sealey,J.E.;Laragh,J.H.
  53. 생리학 강두희
  54. J Nutr v.97 Effects of previous calcium intake on adaptation to low and high calcium diets in rats Benson,J.D.;Emery,R.S.;Thomas,J.W.
  55. Am J Physiol v.218 Role of parathyroid hormone in calcium homeostasis and metabolism Sammon,P.F.;Stacey,R.;Bronner,F.
  56. Poult Sci v.52 Calcium metabolism in the laying hen. Ⅳ. The calcium status of the hen at night Roland,D.A.;Sloan,D.R.;Harms,R.H.
  57. Am J Clin Nutr v.52 Chesnut Ⅲ CH. Factors that influence peak bone mass formation : A study of calcium balance and the inheritance of bone mass in adolescent females Matkovic,V.;Fontana,D.;Tominac,C.;Goel,P.