This paper is concerned with a method for calibrating five-hole probes of both angle-tube and prismatic geometries to measure local total and static pressures and the magnitude and direction of the mean velocity vector. Descriptions of the calibration technique, the typical calibration data, and an accompanying discussion of the interpolation procedure are included. The flow properties are determined explicitly from measured probe pressures using calibration data. Flow angles are obtained within the deviation angle of 1.0 degree and dynamic pressures within 0.03 with 95% certainty. The variations in the calibration data due to Reynolds number are also discussed. For the range of Reynolds number employed, no effect was detected on the pitch, yaw and total pressure coefficients. However, the static pressure coefficient showed change to cause minor variations in the magnitude of the calculated velocity vector. To account for these variations, average correction factors need to be incorporated into the static pressure coefficient.