Protective Effect of Korean Red Ginseng against Oxidative Damage by Carbon Tetrachloride in Rat

흰 쥐에서 사염화탄소에 의한 산화적 손상에 대한 홍삼의 방어효과

To investigate the protective effect of Korean red ginseng (RG) against oxidative damage, rats were intoxicated by carbon tetrachloride and liver tissues and blood were taken and analyzed histopathologically and biochemically. Light microscopy of the liver showed that RG prevented the necrosis of hepatocytes remarkably and reduced the change of fat. RG increased the capability for serum to suppress oxygen radical in the generating system. It is suggested that RG enhanced the antioxidative potential of the body against $CCl_4$, which would prevent the necrosis of hepatocytes in vivo.