Preventive Nutrition and Food Science

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
권호 표지

The Effect of Vitamin {TEX}$B_{6}${/TEX} Deficiency and Age on Plasma Cholesterol Profile in Intensely Exercised Rats

  • Cho, Youn-Ok (Dept. Food and Nutrition, Duksung Women's University, Seoul 132-714)
  • Published : 1996.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study was to determine whether vitamin {TEX}$B_{6}${/TEX} deficiency and age affect the blood cho-lesterol profile in exercising rats. Fifty four rats were fed either a viramin {TEX}$B_{6}${/TEX} deficient dief(-{TEX}$B_{6}${/TEX}) of a control diet(+{TEX}$B_{6}${/TEX}) for 6 weeks, then subdivided into 3 groups:non-exercise group(NE), exercise and sacrifice group(ES), exercise and recuperation group(ER). ES group was exercised in treadmill({TEX}$10^{o}${/TEX}, 0.5~0.8km/h) for 2 hours and sacrifice. ER group was recuperated three days with respective diet after exercise. At week 3 and 6, and level of plasma total cholesterol(TC), high density lipoprotein cholesterol(HDL_C) and low density lipoprotein cholesterol(LDL_C) were compared. In NE group, there was no difference in the levels of TC, HDL_C and LDL_C between +{TEX}$B_{6}${/TEX} rats and -{TEX}$B_{6}${/TEX} rats. The plasma levels of TC and LDL_C of 6 weeks were higher than those of 3 weeks and on difference in HDL_V between 3 weeks rats and 6 weeks rats. In ES group, there was also no difference in the levels of TC, HDL_C and LDL_C between +{TEX}$B_{6}${/TEX} rats and -{TEX}$B_{6}${/TEX} rats and there was no difference in TC, LDL-cholesterol between 3 weeks rats and 6 weeks rats. The level of HDL_C pf 6 weeks was lower than that of 3 weeks rats. In ER group, there was no difference in the levels of TC and LDL_C not only between +{TEX}$B_{6}${/TEX} rats and-{TEX}$B_{6}${/TEX} rats but also between 3 weeks rats and 6 weeks rats. The level of HDL_C was lower in -{TEX}$B_{6}${/TEX} rats than in +{TEX}$B_{6}${/TEX} rats and higher in 6 weeks rats than in 3 weeks rats. These results suggest that vitamin {TEX}$B_{6}${/TEX} deficiency may affect the HDL_C during exercise and after recuperation. The desirable effect of exercise on plasma Cholesterol profile is strengthened in adult age than young age.

Keywords

References

  1. Handbook of vitamins (2nd ed.) Vitamin $B_6$ Leklem,J.E.;Machlin,L.J.(ed.)
  2. J. Natural Sci. The studies on vitamin $B_6$ status in Korean men Song,Y.;Cho,Y.
  3. Atherosclerosis v.66 Diets realistic for westernized people significantly effect lipoproteins, calcium, zinc, vitamin C, vitamin E, vitamin $B_6$ and hematology in vervet monkeys Fincnam,J.E.;Faber,M.;Weight,M.J.;Labadarious,D.;Taljaard,J.J.F.;Steytler,J.G.;Jacobs,P.;Kritchevsky,D.
  4. J. Nutr. Sci. Vitaminol. v.23 Effect of pyridoxine-deficiency on cholesterogenesis in rats fed different levels of protein Okada,M.;Iwami,T.
  5. J. Nutr. Sci. Vitaminol. v.26 Liver 3-hydroxy-3-met-hylglutarylcoenzyme A reductase activity in pyridoxine-deficient rats Gomikawa,S.;Okada,M.
  6. J. Nutr. Sci. Vitaminol. v.28 Role of glucose on fatty liver formation in pyridoxine deficient rats Suzuki,K.;Okada,M.
  7. J. Nutr. Sci. Vitaminol. v.28 Alterations of phospholipid and triglyceride metabolism in fatty liver caused by pyridoxine deficiency in rats Suzuki,M.;Okada,M.
  8. Am. J. Clin. Nutr. v.52 Reducing-diet and exercise-training effects on serum lipids and lipoproteins in mildly obese women Nieman,D.C.;Haig,J.L.;Fairchild,K.S.;DeGuta,E.D.;Dizon,G.P.;Register,U.D.
  9. Metabolism. v.34 The effects of exercise and weight loss on plasma level lipids in young obese men Sopko,G.;Leon,A.S.;Jacobs,D.R.
  10. Metabolism. v.36 The independent effects of dietary weight loss and aerobic training on high density lipoproteins and apolipoprotein A-I concentrations in obese men Schwartz,R.S.
  11. JAMA v.254 Differential effects of exericise on serum lipid and lipoprotein levels seen with changes in body weight : A meta analysis Tran,Z.V.;Weltman,A.
  12. Nutritional assessment of elderlly populations measure and function B vitamer as risk factors for age-related diseases Jacques,P.J.;Riggs,K.M.
  13. Am. J. Clin. Nutr. v.58 Vitamin requirements of elderly people : an update Russel.R.M.;Suter,P.M.
  14. Lancet v.236 Effect of vitamin $B_{12}$, folate and vitamin $B_6$ suppliments in elderly people with normal serum vitamin concentration Naurath,H.J.;Joosten,E.;Riezler,R.;Stabler,S.P.;Allen,R.H.;Lindenbaum,J.
  15. J. Nutr. v.107 Report of the American Institute of Nutrition. Ad Hoc Committee. On standards for untritional studies American Institute of Nutrition
  16. J. Nutr. v.110 Second report of the Ad Hoc Committee. On standards for nutritional studies American Institute of Nutrition
  17. Clin. Chem. v.18 Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge Friedwald,T.;Levy,R.;Friedrickson,D.
  18. Base manual 2.0 Statistical Packages for Social Sciences
  19. J. Nutr. v.72 The effect of pyridoxine on cholesterol metabolism Shah,S.N.;Johnston,P.V.;Kummerow,F.A.
  20. J. Nutr. v.74 Tissue lipid fatty acid composition in pyridoxine-deficient rats Swell,S.;Saw,M.D.;Schools,P.E.Jr.;Treadwell,C.R.
  21. J. Nutr. v.104 Triglyceride metabolism in pyridoxine-deficient rats Audet,A.;Lupien,P.J.
  22. Physic Sports Med. v.8 Exercise and HDL-cholesterol in middle aged men Hartung,G.H.;Squires,W.G.
  23. Annals of the New York Academy of Sciences v.301 Plasma lipoprotein distribution in male and female runners Wood,P.;Hakell,W.
  24. Kor. J. Nutr. v.29 The effect of vitamin $B_6$ deficiency on the utllization of fuel and blood cholesterol profile with regular exercise-training in rats Cho,Y.
  25. Am. J. Clin. Nutr. v.38 Increased plasma pyridoxal 5'-phosphate and vitamin $B_6$ in male adolescents after a 4500 meter run Leklem,J.E.;Shultz,T.D.
  26. Am. J. Clin. Nutr. v.46 Vitamin $B_6$ metabolism as affected by exercise in trained and untrained women fed diets differing in carbohydrate and vitamin $B_6$ content Manore,M.M.;Leklem,J.E.;Walter,M.D.
  27. JADA v.90 Bringing the cholesterol message to the public Yetiv,J.Z.;Del Tredic,A.M.
  28. Biochem. v.29 Uptake of cholesterol by small intestinal brush border membrane is protein-mediated Thurmgofer,H.;Hauser,H.
  29. J. Clin. Invest. v.81 Lowering cholesterol. Havel,R.J.
  30. Nutritional Biochemistry Brody,T.