Bulletin of the Korean Chemical Society

  • 제17권9호
  • /
  • Pages.831-835
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  • 1996
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Synthesis and Reaction of Novel Tricyclic Dynemicin A Models with Methyl Group

  • 발행 : 1996.09.20
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초록

New dynemicin A mimics with methyl group 2a and 2b were synthesized, and acid-induced hydrolyzed to see an electronic effect of substituent for epoxide opening. The model 2a with methyl group at C3 position was more rapidly transformed to diol 16a than 2b with methyl group at C2. This result suggests that any substituent at C3 position plays more important role than any substituent at C2 position in the dynemicin A mimic activation.

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참고문헌

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