Korean Journal of Veterinary Research (대한수의학회지)
- Volume 36 Issue 3
- /
- Pages.615-619
- /
- 1996
- /
- 2466-1384(pISSN)
- /
- 2466-1392(eISSN)
Haptoglobin as an early indicator of infection in pigs
돼지에서 감염의 조기진단 지표로서의 Haptoglobin 적용에 관한 연구
-
Moon, Jin-san
(National Veterinary Research Institute, RDA)
;
-
Nam, Hyang-mi
(National Veterinary Research Institute, RDA)
;
-
Ku, Bok-gyeong
(National Veterinary Research Institute, RDA)
;
- Joo, Yi-seok (National Veterinary Research Institute, RDA) ;
- Jung, Suk-chan (National Veterinary Research Institute, RDA) ;
- Kim, Jong-yeom (National Veterinary Research Institute, RDA) ;
-
Park, Yong-ho
(College of Veterinary Medicine, Seoul National University)
-
문진산
(농촌진흥청 수의과학연구소)
;
-
남향미
(농촌진흥청 수의과학연구소)
;
-
구복경
(농촌진흥청 수의과학연구소)
;
- 주이석 (농촌진흥청 수의과학연구소) ;
- 정석찬 (농촌진흥청 수의과학연구소) ;
- 김종염 (농촌진흥청 수의과학연구소) ;
-
박용호
(서울대학교 수의과대학)
- Received : 1996.01.29
- Published : 1996.09.25
Abstract
Sera of pigs with clinically normal and infectious conditions were analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE) to demonstrate the specific changes in protein profile. In the sera from pigs with infection, haptoglobin with a 40KDa protein was found to be increased as compared to that of sera from normal pigs. As a rapid detection method for monitoring infections at large-scale farms, one of acute phase protein, haptoglobin, was selected to compare the concentrations between infectious and non-infectious conditions. Haptoglobin concentrations were low in pigs with clinically normal conditions but significantly increased in pigs with Aujesky's disease, hog cholera and parvo-virus infection. The studies provide that haptoglobin can be used as an indicator to monitor infections early at farm level.