Pulmonary Cryptococcosis

좌하엽 폐침윤

  • Kim, Gye-Su (Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine) ;
  • Lee, Jae-Cheol (Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine) ;
  • Lee, Seung-Jun (Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine) ;
  • Yoo, Chul-Gyu (Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine) ;
  • Kim, Young-Whan (Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine) ;
  • Han, Sung-Koo (Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine) ;
  • Shim, Young-Soo (Department of Internal Medicine and Tuberculosis Research Institute, Seoul National University College of Medicine)
  • 김계수 (서울대학교 의과대학 내과학교실 및 결핵연구소) ;
  • 이재철 (서울대학교 의과대학 내과학교실 및 결핵연구소) ;
  • 이승준 (서울대학교 의과대학 내과학교실 및 결핵연구소) ;
  • 유철규 (서울대학교 의과대학 내과학교실 및 결핵연구소) ;
  • 김영환 (서울대학교 의과대학 내과학교실 및 결핵연구소) ;
  • 한성구 (서울대학교 의과대학 내과학교실 및 결핵연구소) ;
  • 심영수 (서울대학교 의과대학 내과학교실 및 결핵연구소)
  • Published : 1996.02.29

Abstract

A previously healthy 59-year old male patient was admitted due to cough and abnormal chest x-ray. Cough started 5 months ago and persisted. Two months before admission, abnormality in chest PA was detected. He had no symptom other than cough. He was nonsmoker and physical examination revealed no abnormal finding. His chest X-ray showed ill-defined $2{\times}1\;cm$ ovoid infiltration in left middle lung field. On chest computed tomography, it was located in the subpleural region of posterobasal segment of left lower lobe. Mediastinal lymphadenopathy was absent. Blood test and sputum examination were not diagnostic. Fluoroscopy-guided percutaneous needle biopsy revealed pulmonary cryptococcosis. After central nervous system involvement was excluded by spinal tap, oral ketoconazole therapy was started. The lesion decreased in size after 8 weeks of therapy and almost disappeared on follow-up chest X-ray 4 months later.

Keywords