Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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Correlatin of Serum Inhibin Concentrations with Results in an Ovarian Hyperstimulation for IVF-ET

체외수정시술을 위한 과배란 유도결과와 혈중 Inhibin의 상관관계

  • Bai, Sang-Wook (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University) ;
  • Jung, Chang-Jin (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University) ;
  • Chang, Kyung-Hwan (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University) ;
  • Lee, Byung-Suk (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University) ;
  • Park, Ki-Hyun (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University) ;
  • Cho, Dong-Jae (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University) ;
  • Song, Chan-Ho (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University)
  • 배상욱 (연세대학교 의과대학 산부인과학교실) ;
  • 정창진 (연세대학교 의과대학 산부인과학교실) ;
  • 장경환 (연세대학교 의과대학 산부인과학교실) ;
  • 이병석 (연세대학교 의과대학 산부인과학교실) ;
  • 박기현 (연세대학교 의과대학 산부인과학교실) ;
  • 조동제 (연세대학교 의과대학 산부인과학교실) ;
  • 송찬호 (연세대학교 의과대학 산부인과학교실)
  • Published : 1996.12.31
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Abstract

Serum inhibin concentrations, determimed by radioimmunoassay, were measured in women undergoing pituitary suppression with Decapeptyl and subsequently ovarian stimulation with Highly Purified-Metrodin(HP-FSH) to appraise follicular development. Early follicular basal serum inhibin level correlated with the number of oocytes retrieved(r=0.89, n=8, p<0.05). The number of oocytes retrieved showed a significant correlation with serum inhibin level on the day of hCG administration(r=0.73, n=8, p<0.05). The number of mature oocytes showed a significant correlation with serum inhibin level on the day of hCG administration(r=0.73, n=8, p<0.05). These data suggest that: (1) In the early follicular phase, basal serum inhibin may be a valid index to predict ensuing follicular growth : (2) In the preovulatory phase, maximum serum inhibin may be one of the indexes of follicular development during hyperstimulation cycles.

Keywords