Korean Journal of Pharmacognosy (생약학회지)
- Volume 28 Issue 3
- /
- Pages.138-142
- /
- 1997
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Antidiabetic Activity of Lycii Fructus
구기자의 혈당강하작용
- Shin, Joon-Su (College of Pharmacy, Seoul National University) ;
- Kim, Kyoung-Soon (College of Pharmacy, Seoul National University) ;
-
Jeong, Gi-Hwa
(College of Pharmacy, Duksung Women's University)
;
-
Cheong, Chun-Sik
(College of Pharmacy, Duksung Women's University)
;
-
Ko, Kwang-Ho
(College of Pharmacy, Seoul National University)
;
-
Park, Jeong-Hill
(College of Pharmacy, Seoul National University)
;
-
Huh, Hoon
(College of Pharmacy, Seoul National University)
;
-
Kim, Bak-Kwang
(College of Pharmacy, Seoul National University)
- 신준수 (서울대학교 약학대학) ;
- 김경순 (서울대학교 약학대학) ;
-
정기화
(덕성여자대학교 약학대학)
;
-
정춘식
(덕성여자대학교 약학대학)
;
-
고광호
(서울대학교 약학대학)
;
-
박정일
(서울대학교 약학대학)
;
-
허훈
(서울대학교 약학대학)
;
-
김박광
(서울대학교 약학대학)
- Published : 1997.09.30
Abstract
To elucidate antidiabetic activity of Lycii Fructus. The extract of the Lycii Fructus was subjected to bioactivity-guided fractionation. The extract of the Lycii Fructus was partitioned suceesively with hexane, dichloromethane, ethylacetate and butanol. The butanol fraction, which is most abundant in the Lycii Fructus was subjected to silica gel column chromatography and resulted in seven fractions namely Fr. I - Fr. VII. Among tested several subfractions, Fr IV. Showed the highest antidiabetic activity in the streptozotocin-induced model rat.