Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Studies on the Constituents of Hibiscus syriacus (I)

무궁화나무의 성분 및 생물활성에 관한 연구(I)

  • Lee, In-Kyoung (Kerea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Ryoo, In-Ja (Kerea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Choung, Dong-Ho (Kerea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Han, Kyou-Hoon (Kerea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Yun, Bong-Sik (Kerea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Yoo, Ick-Dong (Kerea Research Institute of Bioscience and Biotechnology, KIST)
  • 이인경 (한국과학기술연구원 생명공학연구소) ;
  • 유인자 (한국과학기술연구원 생명공학연구소) ;
  • 정동호 (한국과학기술연구원 생명공학연구소) ;
  • 한규훈 (한국과학기술연구원 생명공학연구소) ;
  • 윤봉식 (한국과학기술연구원 생명공학연구소) ;
  • 유익동 (한국과학기술연구원 생명공학연구소)
  • Published : 1997.09.30
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Abstract

Hibiscus syriacus L. (Malvaceae) is widely distributed over Korean, China, India and Siberia. The dried flower of Hibiscus syriacus is used as a folk medicine for curing of hematochezia, dysentery, obstruction due to wind-phlegm, regurgitation, and vomiting of food, and the dried root bark is used antipyretic, anthelmintic and antifungal agents. From a chloroform extract of root bark of this plant, compound I, II, and III were isolated and the structures were elucidated by various spectroscopic analyses. These compounds were identified as syringaresinol. E-N-feruloyltyramine, and Z-N-feruloyltyramine, respectively and were isolated from this plant for the first time. Compound II and III exhibited lipid peroxidation inhibitory activities with $IC_{50}$ of 15.5 and 28.6 ${\mu}g/ml$, respectively.

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