Journal of Society of Preventive Korean Medicine (대한예방한의학회지)

Society of Preventive Korean Medicine (대한예방한의학회)
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Antitoxic Effects of Herba Taraxaci Water Extracts Against Cadmium Toxicity in Rats

포공영(蒲公英) 전탕액(煎湯液)을 이용한 카드뮴 독성 해독(解毒) 효과연구

  • Park Jae-Soo (Department of Oriental Medicine, Wonkwang University) ;
  • Lee Jong-Sub (Graduate School, Wonkwang University) ;
  • Lee Gi-Nam (Department of Oriental Medicine, Wonkwang University)
  • 박재수 (원광대학교 한의과대학 예방의학교실) ;
  • 이종섭 (원광대학교 의과대학 예방의학교실) ;
  • 이기남 (원광대학교 한의과대학 예방의학교실)
  • Published : 1997.12.29
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Abstract

A study on the antitoxic effects of Herba Taraxaci extracts against Cadmium Chloride Toxicity in Rats. This study was performed to find out the effect of taraxacum platy carpum against Cadmium toxicity. The experimental rats were divided into 5 groups such as control group, Cadmium alone treatment group, three simultaneous treatment groups of taraxacum platy carpum and cadmium. Rat were given pellets administration with three dosage of taraxacum platy carpum such as 4 mg/kg body weight for four weeks. The results were summarized as follows on: 1. The simultaneously administration of taraxacum platy carpum and cadmium significantly more decreased cadmium concentration in liver and kidney tissues compared to the administration of cadmium alone. (p<0.05) 2. The simultaneously administration of taraxacum platy carpum and cadmium significantly more increased metallothionein concentration in liver and kidney tissues compared to administration alone. (p<0.05) 3. When liver and kidney tissues were observed with optical microscope obvious changes were visible in those tissue.

Keywords

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