Archives of Pharmacal Research
- Volume 20 Issue 1
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- Pages.39-45
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- 1997
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Effects of I.C.V Administration of Ethylcholine Aziridinuim(AF64A) on the Central Glutamatergic Nervous Systems in Rats
- Ma, Young (College of Pharmacy, Chonnam National University) ;
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Lim, Dong-Koo
(College of Pharmacy, Chonnam National University)
- Published : 1997.02.01
Abstract
Changes in glutamatergic nervous activities following intracerebroventricular (icv) administration of ethylcholine aziridinium (AF64A) were studied in rats. The levels of total glutamate, those of glutamate in cerebrospinal fluid (CSF) and in extracellular fluid (ECF) of striatum, the activities of glutamine synthetase (GS), glutaminase and glutamate dehydrogenase (GDH) and the specific binding sites of