Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
권호 표지

Effect of Dietary Calcium Levels on Peak Bone Mass Formation in Growing Female Rats

칼슘 섭취 수준이 성장기 암컷 흰쥐의 최대골질량 형성에 미치는 영향

  • 이연숙 (서울대학교 농가정학과) ;
  • 박미나 (서울대학교 농가정학과) ;
  • 김은미 (한양대학교 식품영양학과)
  • Published : 1997.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

The present study was designed to examine how Ca intake contributes to the increase of peak bone mass with growing female rats. Weaned rats were fed experimental diets consisting in five levels of Ca; very low(0.1%), low(0.2%), moderate(0.5%), high(1.0%) and very high(1.5%) for 4, 8 and 12 weeks. Bone growth, metabolism and Ca metabolism were determined. As for the rats fed for 4 weeks, the bone weight, length and breaking force and bone metabolism were not significantly affected by dietary Ca levels, whereas the current intakes of Ca were observed to have significantly affected the rats fed for 8 or 12 weeks with regard to the bone weight, length and breaking force and bone metabolism. The bone ash and Ca contents of the rats were affected by dietary Ca levels for the total period of feeding. It is suggested that dietary Ca itself affected the mineralization process either during the growth or later, although the resulting bone mass is not a linear function of dietary Ca content.

Keywords

References

  1. New Engl. J. Med. v.327 Calcium intake and peak bone mass Matkovic, V.
  2. Bone Miner. v.23 Development of bone mass and bone density of the spine and femoral neck - a prospective study of 65 children and adolescents Kroger, H.;Kotaniemi, A.;Kroger, L.;Alhava , E.
  3. J. Clin. Endocrinol. Metab. v.75 Longitudinal monitoring of bone mass accumulation in healthy adolescents: evidence for a marked reduction after 16 years of age at the levels of lumbar spine and femoral neck in female subjects Thenitz, G.;Buchs, B.;Rizzoli, R.;Slosman, D.;Clavien, H.
  4. Ann. Rev. Nutr. v.13 Nutritional factors in osteoporosis Heaney, R. P.
  5. Am. J. Clin. Nutr. v.32 Bone status and fracture rates in two regions of Yugoslavia Matkovic, V.;Kostial, K.;Simonovic, I.;Buzina, R.;Brodarec, A.;Nordin, B. E. C.
  6. Am. J. Clin. Nutr. v.42 Postmenopausal bone density and milk consumption in children and adolescence Sandler, R. B.;Slemenda, C. W.;Laporte, R. E.
  7. New Engl. J. Med. v.327 Calcium supplementation and icnreases in bone mineral density in children. Johnston, C. C.;Miller, J. Z.;Slemenda, C. W.;Reister, T. K.;Hui, S.;Christian, J. C.;Peacock, M.
  8. Am. J. Clin. Nutr. v.54 Influence of calcium intake and growth indexes on vertebral bone mineral density in young females Sentipal, J. M.;Wardlaw, G. M.;Mahan, J.;Matkovic, V.
  9. J. Bone Miner. Res. v.10 Alterations in calcium intake on peak bone mass in the female rat Peterson, C. A.;Eurell, J. A. C.;Erdman, J. R.
  10. Bone Miner. v.12 Calcium metabolism and bone mineralization in female rats fed diets marginally sufficient in calcium : effects of increased dietary calcium intake Thomas, M. L.;Simmons, D. J.;Kidder, L.;Ibarra, M. J.
  11. Calif. Tissue Res. v.22 Influence of calcium intake, age and sex on bone Matkovic, V.;Kostial, K.;Sinonovic, I.;Brodarec, A.;Buzina, R.
  12. J. Nutr. v.107 Report of the American Institute of Nutrition Ad Hoc Commitee on standards for nutrition studies Report of the American Institute
  13. Anal. Chem. v.35 Two improved and simplified methods for the spectrophotometric determination of hydroxyproline Bergman, I. B.;Loxley, R.
  14. J. Physiol. v.100 Strength and size of bone in relation to calcium intake Bell, G. H.;Orr, J.
  15. Am. J. Physiol. v.225 Decreased bone formation, mineralization and enhanced resorption in calcium-deficient rats Stauffer, M.;Baylink, D.;Wergedal, J.;Rich, C.
  16. Clinical biochemical and hematological reference values in normal experimental animals and normal humans(2nd ed.) Mitruka, B. M.
  17. J. Nutr. v.124 Bone repair in calcium-deficient rats: Comparison of xyritol+Calcium carbonate with calcium carbonate, calcium lactate and calcium citrate on the replecation of calcium Hamalainen, M. M.
  18. Arch. Toxiol. v.39 strudies of rat alkaline phosphatase Pickering, R. G.;Pickering, C. E.
  19. J. Nutr. v.118 The effect of dietary calcium on bone metabolism in young and aged female rats using a short-term in vivo model Sinha, R.;Smith, J. C.;Soares, J. H.
  20. New Engl. J Med. v.268 Urinary hydroxyproline as an index of collagen turnover in bone Dull, T. A.;Henneman, P. H.
  21. J. Clin. Pathol. v.35 Measurement of the fasting urinary hydroxyproline: creatinine ratio in normal adults and its variation with age and sex Hodgkinson, A.;Thompson, T.
  22. Clin. Achem. Acta v.64 A simplified method for the estimation of urinary total hydroxyproline Nobbs, B. T.;Walker, A. W.;Davies, T. J.
  23. Bone Miner. v.11 The ovariectomized, lactating rat as an experimental model for osteopenia : calcium metabolism and bone changes Anderson, J. J. B.;Garner, S. C.;Mar, M. H.;Boass, A.;Toverud, S. U.;Parikh, I.