Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effect of Acron Extracts on the Antioxidative Enzyme System

도토리추출물이 흰쥐의 체내 항산화효소계에 미치는 영향

  • 성인숙 (영남대학교 식품영양학과) ;
  • 박은미 (영남대학교 식품영양학과) ;
  • 이미경 (영남대학교 식품영양학과) ;
  • 한은경 (영남대학교 식품영양학과) ;
  • 장주연 (영남대학교 식품영양학과) ;
  • 조수열 (영남대학교 식품영양학과)
  • Published : 1997.06.01
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Abstract

This study was conducted to investigate the effect of acorn extracts on the antioxidative enzyme system. Male Sprague-Dawley rats(110$\pm$10g) were fed on containing normal and high fat diets. They were orally administrated (0.02g/100g B.W) of acorn ethylacetate-extract and water-extract at the same time once a day, respectively. Net weight gain and feed efficiency ratio were increased in high fat diet groups and decreased by acorn extracts administration. The effect of acorn extracts on hepatic glutathione peroxidase(GSH-Px), glutathione S-transferase(GST) and catalase activities did not show significancy in normal fat diet groups. GST and catalase activities and lipid peroxidation content(LPO) were significantly increased in high fat diet groups and this increment were decreased by acorn extracts administration. However GSH-Px activity and GSH content were decreased in high fat diet groups but increased by acorn extracts administration. The activities of lactate dehydrogenase(LDH), alkaline phosphatase(ALP) and aminotransferase in serum were significantly increased in high fat diet group but these increment reduced in acorn extracts administration groups. These results indicate that acorn extracts could improve the liver function and prevent the metabolic diseases by hyperlipidemia.

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References

  1. 한국영양식량학회지 v.24 녹차, 오룡차 및 홍차 추출물의 xanthine oxidase 억제 작용 여생규;박영범;김인수;김선봉;박영호
  2. 한국영양식량학회지 v.20 에탄올 공급이 흰쥐의 조직 중 glutathione 및 지질산화 수준에 미치는 영향 이정원
  3. 한국영양식량학회지 v.23 과산화지질의 투여가 흰쥐 간의 산화와 항산화계에 미치는 영향 권명자;전영수;송영옥
  4. J. Agric. Food Chem. v.27 Lipid hydroperoxides reactivity with protein and acids. A. review Gardner, H. W.
  5. J. Nutr. Sci. Vitaminol. v.29 Dietary effect of ω-3 type polyunsaturated fatty acids on serum and liver lipid levels in rats Kobatake, Y.
  6. 약학회지 v.38 도토리에서 분리한 Dotorioside Ⅰ,Ⅱ의 구조 임광식;손미정;이시강
  7. 한국영양식량학회지 v.21 도토리 gallic acid의 항산화성 이미현;정재홍;오만진
  8. 한국농화학회지 v.33 지방함량에 따른 도토리 전분의 이화학적 특성 안호경;길훈배;유해의;오두환
  9. 한국농화학회지 v.33 탄닌 함량에 도토리 전분의 물리화학적 특성 안호경;최형택;김병용;오두환
  10. 한국농화학회지 v.35 묵 형성 전분의 특성에 대한 연구 권미라
  11. 한국영양학회지 v.17 도토리 전분의 tannin 성분과 물리적 특성에 관한 연구 박재영;구성자
  12. 한국식품과학회지 v.5 미생물 tannase에 의한 식품의 tannin 성분 분해에 관한 연구 채소규;유태정
  13. 약학연구지 v.16 도토리의 tannin 성분에 관한 화학적 연구 김기현
  14. 고려대농림논집 v.24 대두유 및 대두유-물 에멀죤 기질에서 각종 페놀화합물의 항산화작용 김동훈;김영희
  15. Food Chemistry v.14 Phenolic acids and related compounds as antioxidants for edible oils Dziezic, S. Z.;Hudson, B. J. F.
  16. 한국농화학회지 v.32 식용 대두유에 대한 phenolics의 항산화 효과 조미자;권태봉;오성기
  17. J. Agric. Food Chem v.30 Vanillin assay for proanthocyanidins (Condensed tannins): modification of the solvent for estimation of the degree of polymerization Butler, L. G.;Price, M. L.;Brotherton, J. E.
  18. J. Biol. Chem. v.193 Protein measurement with the folin phenol reagent Lowry, O. H.;Rosbrough, N. J.;Farr, A. L.;Randall, R. J.
  19. J. Lab. Clin. Med. v.70 Studies on the quantitative and qualitative characterization of erythrocytes glutathione peroxidase Paglia, E. D.;Valentine, W. N.
  20. Methods of enzymatic analysis Catalase Aebi, H.;Vergmeyer, H. U.(ed.)
  21. J. Biol. Chem. v.249 Glutathione S-transferases : The first enzymatic step in mercapturic acid formation Habig, W. H.;Pabist, M. J.;Jakoby, W. B.
  22. Anal. Biochem. v.95 Assay for lipids peroxides in animal tissues by thiobarbituric acid reaction Ohkawa, H.
  23. Arch. Biochem. Biophy. v.82 Tissue sulfhydryl group Ellman, G. L.
  24. Sigma Tech. Bull. v.500 Berga, L.;Broida, D.
  25. J. Clin. Pathol. v.7 Estimation of plasma phosphatase by determination of hydrolyzed with amino antipyrene Kind, P. R. N.;King, E. T.
  26. Am. J. Clin. Pathol. v.28 A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminase Reitman, S.;Frankel, S.
  27. Statiatical method. 6th. Snedecor, G. W.;Cochrane, W. G.
  28. Proc. Natl. Acad. Sci. U.S.A. v.80 Modulation of proline-rich protein biosynthesis in rat parotid glands by sorghums with high tannin levels Mehansho, H.;Hagerman, A.;Clements, S.;Butler, L.;Rogler, J.;Mcarlson, D.
  29. Eur. J. Clin. Nutr. v.48 Dietary fats and gastrointestinal function Dodge, J. A.
  30. British J. Nutr. v.55 The role of condensed tannins in the nutritional value of Lotus pedunculatus for sheep Barry, T. N.;Manley, T. R.;Duncan, S. J.
  31. J. Nutr. v.65 Activities of enzymes of the pancreas and the lumens and mucosa of the small in growing broiler cockerels fed on tannin-containing diet Ahmed, A. E.
  32. J. Nutr. v.109 Influence of Tannin-rich Carob Pod fiber on the cholesterol metabolism in the rat Wursch, P.
  33. J. Nutr. v.107 Tannic acid and oxidized tannin acid on the functional state of rat intestinal epithelium Mitjavila, S.;Lacombe, C.;Larrera, G.;Derache, R.
  34. Am. J. Clin. Nutr. v.60 Effect of fats and fatty acids on blood lipid in humans an overview Martijn, B. K.;Peter, L. Z.;Ronald, P. M.
  35. J. Nutr. v.111 Modes of action of gallic acid in suppressing food intake of rats Glick, Z.
  36. Biochem. Pharmacology v.42 Effect of ethanol on Cd-induced lipid peroxidation and antioxidant enzymes in rat liver Geeta, S.;Ravindra, N.;Kiran, D. G.
  37. J. Nutr. v.121 Changes In colonic antioxidant status in rats during long-term feeding of different high fat diets Connye, K.;Barbara, C. P.
  38. Methods in Enzymology v.77 Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples Akerboom, T. P. M.
  39. Lipids v.27 Glutathione and antioxidants protect microsomes against lipid peroxidation and enzyme inactivation Miao, L. H.;Al, L. T.
  40. J. Nutr. v.118 Rapid autooxidation of fish oil in diets without added antioxidants Fritche, K.;Johnston, P. V.
  41. Proceedings of the American association for cancer research v.36 Characterization of the tumor-promoting activity of thapsigargin in Sencar mouse skin and its modulation by gallotannin Perchellet, J. P.;Gao, X. M.;Perchellet, E. M.;Gali, H. U.;Newell, S. W.;Chen, G.;Bottari, V.
  42. Mutation Res. v.303 The protective role of gallic acid ester in bacterial cytotoxicity and SOS responses induced by hydrogen peroxide Tsutomu, N.;Hiramitsu, M.;Osawa, T.;Kawakishi, S.
  43. Arch. Toxicol. v.69 Cytotoxicity of propyl gallate and related compounds in rat hepatocytes Nakagawa, Y.;Tayama, S.
  44. J. Nutr. v.107 Tannic acid and oxidized tannic acid on the functional state of rat intestinal epithelium Mitjavila, S.
  45. 고려대논집 v.25 유지첨가 급식이 체내대사에 미치는 영향 홍윤식
  46. 한국영양학회지 v.20 알콜과 식이지방량이 흰쥐의 성장, 간기능 및 혈액의 생화학적 특성에 미치는 영향 최영신;정경희;조성희
  47. J. Ethnopharmacol. v.14 Antihepatotoxic actions of tannins Hikino, H.;Kiso, Y.;Hatano, T.;Yoshida, T.;Okuda, T.