Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Genotoxicological Safety of the Gamma Irradiated Medicinal Herbs in the salmonella typhimurium Reversion Assay

복귀돌연변이시험을 이용한 감마선조사 생약재의 안전성에 관한 유전독성학적 평가

  • 조성기 (한국원자력연구소 방사선식품공학연구팀) ;
  • 육홍선 (한국원자력연구소 방사선식품공학연구팀) ;
  • 변명우 (한국원자력연구소 방사선식품공학연구팀)
  • Published : 1997.10.01
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Abstract

The three medicinal herbs-Curcuma longa Linne, Paeonia japonica Miyabe, Scutellaria baikalensis George-irradiated with gamma rays have been tested for their possible genotoxicity. The methanol-soluble and water-soluble fractions of the 10kGy gamma-iradiated herbs were examined in the Salmonella typhimurium histidine reversion assy(Ames test) using S. typhimurium TA98, TA100 and TA102 as tester strains. No mutabenicity was detected in this assay with or without metabolic activation. The safety of the herbs irradiated with gamma rays at practical doses needs to be evaluated in further tests of genotoxicity in vivo and chronic and reproductive toxicity.

Keywords

References

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