한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)
- 제12권1호
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- Pages.1-8
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- 1997
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- 1229-1153(pISSN)
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- 2465-9223(eISSN)
엉겅퀴에서 분리 정제한 Silymarin의 사람 Low Density Lipoprotein에 대한 항산화 효과
Antioxidative Effect of Silmarin Purified from Silybum Marianum on Modificaion of Human Low Density Lipoprotein
초록
This study was performed to evaluate the antioxidant activity of silymarin against human low density lipoproteins(LDL) oxidation. Silymarin extracted from Silybum marianum was successively purified with solvent fractionation and followed by silica gel column chromatography. The active substances were separated by HPLC and the isolated active substances, silymarin were identified by IR, NMR, GC-MS as silymarin. Silymarin inhibited at the 5