Journal of Periodontal and Implant Science
- 제27권4호
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- Pages.805-818
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- 1997
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
Substance P가 T 임파구의 세포증식과 IL-2 생산에 미치는 영향
Effects of Substance P on the Cell Proliferation and IL-2 Production of T Lymphocyte
- 문진균 (전북대학교 치과대학 치주과학교실, 전북대학교 치의학 연구소) ;
- 최병선 (전북대학교 치과대학 치주과학교실, 전북대학교 치의학 연구소) ;
- 이석초 (전북대학교 치과대학 치주과학교실, 전북대학교 치의학 연구소) ;
- 김형섭 (전북대학교 치과대학 치주과학교실, 전북대학교 치의학 연구소)
- Moon, Jin-Kyun (Department of Periodontology, College of Dentistry, Chon-buk National University) ;
- Choi, Byung-Son (Department of Periodontology, College of Dentistry, Chon-buk National University) ;
- Lee, Seok-Cho (Department of Periodontology, College of Dentistry, Chon-buk National University) ;
- Kim, Hyung-Seop (Department of Periodontology, College of Dentistry, Chon-buk National University)
- 발행 : 1997.12.31
초록
Immune responses of periodontal tissue may be regulated by products of sensory afferent nerve endings such as neuropeptides. Substance P(SP), a tachykinin neuropeptide, has been previously reported to stimulate the activities of T lymphocyte. Therefore, I examined the role of SP in IL-2 production and cell proliferation by using a homogeneous line of T lymphocytes(Jurkat and HuT78). Cell proliferation rate was determined by [
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