생약학회지 (Korean Journal of Pharmacognosy)
- 제29권4호
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- Pages.277-282
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- 1998
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
백자인(栢子仁)으로부터 항Herpes 바이러스 1형(HSV-1) 물질의 분리
Isolation of Anti-Herpes Simplex Virus Type 1(HSV-1) Component from Thujae orientalis Semen
- 강은정 (한국한의학연구원 연구부) ;
- 강봉주 (한국한의학연구원 연구부) ;
- 박갑주 (한국한의학연구원 연구부) ;
- 고병섭 (한국한의학연구원 연구부) ;
- 김호경 (한국한의학연구원 연구부)
- Kang, Eun-Jung (Department of Research, Korea Institute of Oriental Medicine) ;
- Kang, Bong-Joo (Department of Research, Korea Institute of Oriental Medicine) ;
- Park, Kap-Joo (Department of Research, Korea Institute of Oriental Medicine) ;
- Ko, Byoung-Seob (Department of Research, Korea Institute of Oriental Medicine) ;
- Kim, Ho-Kyoung (Department of Research, Korea Institute of Oriental Medicine)
- 발행 : 1998.12.30
초록
In order to search for anti-Herpes simplex virus type 1(HSV-1) agents, we screened 80 specimens of Korean traditional medicine by SRB assay. The methanol extracts of Thujae orientalis Semen (Cupressaceae) showed strong anti-HSV activity among samples tested. From the butanol fraction of Thujae orientalis Semen anti-HSV-1 agent was isolated by chromatographic separation using Amberlite XAD-4 and Sephadex LH-20. The structure was elucidated by spectroscopic methods, and was identified as
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