Journal of Acupuncture Research

  • 제15권2호
  • /
  • Pages.17-28
  • /
  • 1998
  • /
  • 2586-288X(pISSN)
  • /
  • 2586-2898(eISSN)
대한침구의학회 (Korean Acupuncture & Moxibustion Medicine Society)
권호 표지

고빈도전침자극(高頻度電鍼刺戟)의 자극시간(刺戟時間)에 따른 중추신경계(中樞神經系) 신경세포(神經細胞)의 활성변화(活性變化)에 미치는 영향(影響)

Effect of stimulation-duration of high frequency electroacupuncture on the neuronal activities in the spinal cord and brainstem using Fos immunohistochemical technique

  • 손성세 (경희대학교 한의과대학 침구학교실) ;
  • 남상수 (경희대학교 한의과대학 침구학교실) ;
  • 이재동 (경희대학교 한의과대학 침구학교실) ;
  • 최도영 (경희대학교 한의과대학 침구학교실) ;
  • 안병철 (경희대학교 한의과대학 침구학교실) ;
  • 박동석 (경희대학교 한의과대학 침구학교실) ;
  • 이윤호 (경희대학교 한의과대학 침구학교실) ;
  • 최용태 (경희대학교 한의과대학 침구학교실)
  • Sohn Sung-Sae (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy) ;
  • Nam Sang-Soo (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy) ;
  • Lee Jae-Dong (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy) ;
  • Choi Do-Young (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy) ;
  • Ahn Byoung-Choul (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy) ;
  • Park Dong-Seok (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy) ;
  • Lee Yun-Ho (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy) ;
  • Choi Yong-Tae (Dept. of Acupuncture & Moxibustion Oriental Medical College, Kyung Hee Univeristy)
  • 발행 : 1998.12.30
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초록

The present study was designed to investigate the effect of different stimulation-duration of high frequency electroacupuncturet(EA) treatment on the neuronal activities in the spinal cord and brainstem using Fos immunohistochemical technique. Three different stimulus-duration was used in this experiment : 30minutes, 1 hour and 2 hours. The summerized results were summerized as follow : 1. The number of Fos expression was significantly increased in the spinal cord dorsal horn depending upon the increase of stimulus-duration (P<0.05). Otherwise, there was no significant difference between 30 minutes EA treated group and anesthetic control. 2. High frequency EA biphasic stimulation significantly enhanced the Fos expression in the DR, middle and rostral portion of PAG LD, and caudal PAG LV after 1 hour and 2 hours treatment. The number of Fos immunoreactive neuron in the brainstem was increased accorcting to the length of stimulus-duration. Those results indicate that at least 1 hour EA treatment was necessary to increase the neuronal activities in the spinal cord and brainstem. Those basic data from this study can be applied to establish the effective treatment of EA for pain control in the clinical field.

키워드

참고문헌

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