Abstract
This histological study was performed to investigate the effects of .Paljeungsan-gagambang on the epididymal fat cell size, number and the fat drop area of hepatic lobule of rats fed High Fat Diet. Paljeungsan-gagambang was orally administered to the rats of sample group 26mg per 200g of rat's weight everyday for 4 weeks, and the control group were just fed with equal amount of saline solution. Then they are the epididymal fat cell size, epididymal fat cell numberand fat drop area of hepatic lobule that were measured. The results were summarized as follows; 1. The size of the epididymal fat cell was decreased significantly as compared with the control group. 2. The number of the epididymal fat cells was decreased significantly as compared with the control group in distribution chart classified by cell size 3. The Area(%) of the Fat drops in the hepatic lobule was decreased significantly as compared with the control group. According to the above results, it is considered that Paljeungsan-gagambang have effects on the decrease of the epididymal fat cell size, number and fat drop area of hepatic lobule of rats fed high fat diet; Thus, the adminisrtation of Paljeungsan-gagambang is considered to have an improving effect on obesities and liver diseases caused by high fat diet.
