대한예방한의학회지 (Journal of Society of Preventive Korean Medicine)

대한예방한의학회 (Society of Preventive Korean Medicine)
권호 표지

녹두(綠豆) 전탕액(煎湯液)의 Rat의 장기(臟器) 조직내(組織內) 카드뮴 독성(毒性) 해독(解毒)에 관한 연구(硏究)

Antitoxic Effects of Semen Mungo Water Extracts against Cadmium Toxicity in Organs of Rats

  • 지정옥 (원광대학교 한의과대학 예방의학교실) ;
  • 김정필 (원광대학교 한의과대학 예방의학교실) ;
  • 이기남 (원광대학교 한의과대학 예방의학교실) ;
  • 이종섭 (원광대학교 의과대학 예방의학교실)
  • Ji Jeong-Ok (Dept. of Preventive Oriental Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Kim Jeong-Pil (Dept. of Preventive Oriental Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Lee Ki-Nam (Dept. of Preventive Oriental Medicine, College of Oriental Medicine, Wonkwang University) ;
  • Lee Jong-Sub (Dept. of Preventive Medicine, College of Oriental Medicine, Wonkwang University)
  • 발행 : 1998.12.29
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초록

A study on the antitoxic effects of Semen Mungo extracts against Cadmium Chloride Toxicity in Rats This study was performed to find out the effect of Semen mungo against Cadmium toxicity. The experimental rats were divided into 5 groups such as control group, Cadmium alone treatment group, three simultaneous treatment groups of semen mungo and cadmium. Rats were given pellets administration with three dosage of semen mungo glabrae such as 4mg/kg body weight for four weeks. The results were summarized as follows on: ' 1. The simultaneously administration of semen mungo and cadmium significantly more decreased cadmium concentration in liver and kidney tissues compared to the administration of cadmium alone.(p<0.05) 2. The simultaneously administration of semen mungo and cadmium significantly more decreased metallothionein concentration in liver and kidney tissues compared to administration of cadmium alone(p<0.05) 3. When liver and kidney tissues were observed with optical microscope obvious changes were visible in those tissues.1

키워드

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