Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Antihyperlipidemic Effects of Methanol Extracts from Mulberry Leaves in Cholesterol-Induced Hyperlipidemia Rats

뽕잎추출물이 콜레스테롤 투여 흰쥐의 혈청지질에 미치는 영향

  • 김선여 (농촌진흥청 농업과학기술원) ;
  • 이완주 (농촌진흥청 농업과학기술원) ;
  • 김현복 (농촌진흥청 농업과학기술원) ;
  • 김애정 (혜전대학 식품영양과) ;
  • 김순경 (순천향대학교 식품영양학과)
  • Published : 1998.12.01
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Abstract

This study was conducted to investigate the effect of mulberry leaves on lipid metabolism in cho lesterol induced hypercholesterolemia rats. The mulberry treatment group showed decreases of serum lipid concentration compared with hyperlipidemic group. Also, Mulberry leaves inhibited the activity of HMG Co A reductase, increased lipase activity. In histopathological examination, abdominal aorta showed no critical lesions with mulberry leaves treatment. These results suggest that hypolipidemic effects of mulberry leaves on rats were the inhibition of cholesterol synthesis and acceleration of cholesterol catabolism in the liver. For human, serum triglyceride contents were more significantly decreased with treatment of mulberry leaves powder.

Keywords

References

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