Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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The Anti-complementary Activity of Exo-polymers Produced from Submerged Mycelial Cultures of Higher Fungi with Particular Reference to Cordyceps militaris

  • Song, Chi-Hyun (Department of Biotechnology, Taegu University) ;
  • Jeon, Young-Jae (Department of Biotechnology, Taegu University) ;
  • Yang, Byung-Keun (Department of Biotechnology, Taegu University) ;
  • Ra, Kyung-Soo (Department of Food and Nutrition, Technical Junior College) ;
  • Sung, Jae-Mo (Department of Agricultural Biology, Kangwon National University)
  • Published : 1998.10.01
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Abstract

The anti-complementary activity (immuno-stimulating activity) was tested for the exo-polymers (extra-cellular polymer) produced from submerged mycelial cultures of 21 types of higher fungi. Anti-complementary activity of the exo-polymer from Cordyceps militaris showed the highest (69.0%) followed by Pleurotus ostreatus (63.7%) and Trametes suaveolens (61.4%). The mycelial growth rate and biomass doubling time of C. militaris in a 5 I air-lift fermenter were 0.0255 $h^{-1}$ and 27.2 h, respectively. The yield of the exo-polymer produced from the culture broth of C. militaris was 2.95 mg of dry weight/ml of culture broth. Sugar and amino acid compositions of this exo-polymer were analyzed.

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