The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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Neurotrophic Factors and Their Roles

신경영양성 인자와 역할

  • Kim Sik-Hyun (Department of Biology Graduate School, Keimyung University) ;
  • Nam Ki-Won (Taegu University Rehabilitation Clinic)
  • 김식현 (계명대학교 자연과학대학원 생물학과) ;
  • 남기원 (대구대학교 재활의원)
  • Published : 1999.08.01
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Abstract

Neurotrophic factors control the survival and differentiation in developing neurons, Furthermore, nut evidence suggests that neurotrophic factors promote the axonal growth and synaptic plasticity In the CNS. Research is currently being undertaken in order to determine whether members of the neurotrophic factor family have potential therapeutic roles in preventing and/or reducing the neuronal cell death and atrophy. This review summarizes the current knowledge of characterized neurotrophic factors including NGF, BDNF, NT-3, and NT-4/5.

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