The Journal of Korean Physical Therapy
- Volume 11 Issue 2
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- Pages.131-137
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- 1999
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- 1229-0475(pISSN)
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- 2287-156X(eISSN)
Neurotrophic Factors and Their Roles
신경영양성 인자와 역할
- Kim Sik-Hyun (Department of Biology Graduate School, Keimyung University) ;
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Nam Ki-Won
(Taegu University Rehabilitation Clinic)
- Published : 1999.08.01
Abstract
Neurotrophic factors control the survival and differentiation in developing neurons, Furthermore, nut evidence suggests that neurotrophic factors promote the axonal growth and synaptic plasticity In the CNS. Research is currently being undertaken in order to determine whether members of the neurotrophic factor family have potential therapeutic roles in preventing and/or reducing the neuronal cell death and atrophy. This review summarizes the current knowledge of characterized neurotrophic factors including NGF, BDNF, NT-3, and NT-4/5.
Keywords