YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Inhibitory Effects of Water-Acetone Extracts of Chestnut inner shell, Pine needle and Hop on The Melanin Biosynthesis

율피.솔잎.호프의 수성 아세톤 추출물에 의한 Melanin 생성 억제 효과

  • 양민진 (동덕여자대학교 보건관리학과) ;
  • 김명길 (경기도 보건환경연구원) ;
  • 임세진 (동덕여자대학교 약하과) ;
  • 안형수 (동덕여자대학교 약하과) ;
  • 안령미 (동덕여자대학교 보건관리학과)
  • Published : 1999.08.01
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Abstract

The skin whitening effects of pine needle extract, hop extract and chestnut inner shell extract were evaluated both in vitro and in B 16 mouse melanoma cell lines. Each extracts significantly inhibited tyrosinase activity, dopa auto-oxidation and melanin biosynthesis in vitro and in B 16 cell lines. In vitro, hop extract inhibited melanin biosynthesis 15 times stronger than kojic acid at $10{\;}\mu\textrm{g}/ml$ concentration. Each extracts were stronger inhibitors of melanin biosynthesis than kojic acid in B 16 mouse melanoma cell at less than $4{\;}\mu\textrm{g}/ml$ concentration. These results show that extracts fo pine needle, hop and chestnut inner shell could be developed as skin whitening component of cosmetics.

Keywords

References

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