생명과학회지 (Journal of Life Science)

  • 제9권5호
  • /
  • Pages.504-509
  • /
  • 1999
  • /
  • 1225-9918(pISSN)
  • /
  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
권호 표지

Xenopus 예정외배엽에서 Activin A와 IGF-1의 복합처리에 의한 기관분화

Organogenesis by Combined-Dose of Activin A and IGF-1 In Xenopus Presumptive Ectoderm

  • 정선우 (창원대학교 자연과학대학 생물학과) ;
  • 이호선 (창원대학교 자연과학대학 생물학과) ;
  • 윤춘식 (대전광역시 생명공학연구소 분자세포생물학연구부)
  • 발행 : 1999.10.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The trend of organogenesis in Xenopus presumptive ectoderm was studied by combined dose of activin A and IGF-1(insulin-like growth factor-1). In reference study of Asashima and his colleagues, the inductive patterns of various organs were reported with activin, the potent mesoderm inducing factor. In present study, the inducing pattern was cleared with combined-dose of concentration 1-100 ng/ml activin A and IGF-1. In addition, the result from single treatment of activin A was compared with former study. As a result, eye was differentiated in 5-20% of explants at 10 and 50 ng/ml concentrative combination of activin A. Otic vesicle was appeared in the entire concentrative combination of IGF-1. Pronephric duct was induced 19-38% of explants at the concentration of activin A 100 ng/ml by adding IGF-1. The comparison of single treatment of activin A was showed some difference in dose-dependent inducing pattern.

키워드

참고문헌

  1. Devlop. Growth & Differ. v.36 no.5 In vitro control of the embryonic from of Xenopus laevis by activin A;time and dose-dependent including properites of actiein treated ectoderm
  2. Roux's Arch. Dev. Biol. v.200 Concentration dependent inducing activity of activin A Ariwzumi, T.;N. Moriya,H.;Uchiyama;M. Asashima
  3. Roux's Arch. Dev. Biol. v.198 Mesodermal induction in early amphibian embryos by activin A(erythroid differentiation factor) Asahima, M.;H. Nakano;K. Shimada;K. Kinoshita;H. Shibia;N. Ueno
  4. Korean J. Life Science v.18 no.5 Pronephros induction by combined dose of activin A and IGF-1 , and high dose effect of IGF-1 in Xenopus animal cap assay Chenog, S. W.;J.H. Jin;C.S. Yoon
  5. the South African clawed frog. Xenopus Deuchar. E.M.
  6. Developemental Biology Gillbert,S.F.
  7. Int. J. Dev. Biol. v.39 Divide, asscumulate, differentiate;cell condensations in skeletal development revisited Hall, B.K.;T. Miyake
  8. Horm.Res. v.42 no.1-2 Insulin and IGF-1 signaling in oocyte maturation Gigorescu, F.; M.T. Baccara;M. Rouard;E. Rendard
  9. Mol. Endocrinol. v.4 no.2 Evolution of insulin-like growth factor I(IGF-1) percursor from Xenopus leavis Kajimoto, Y.;P. Rotwein
  10. Xenopus leavis;practcal used in cell and molecular biology Methods in cell bology Kay, B.K.;H. Peng
  11. Development v.121 Effect of acdtivin and lithium on isolated Xenopus animal blastomeres and response alternation at the midblastula transition Kinoshita, K.;M. Asahima
  12. CMLS. Cell. Mol, Life Sci. v.53 An essay on the similarities and differences between inductive interactions in anuran and urodele embroyos Malacinski,G.M.;T. Bessho;C. Yokota;A. Fukui;M. Asashima
  13. Develop. Genes and Evolution v.207 Inductive interaction of blood cells in Xenpous embryo explants Miyanaga, Y.;R. Shiurba;S. Nagata;J. Pfeiffer;M. Asashima
  14. Normal table of Xenpous laevis External and internal stege criteria in the development Xenpous laevis NieuwoopP.D.;J. Faber
  15. Science v.233 Regulation by growth hormone number of chondrocytes containing IGF-1 in rat growth plate Nilsson. A.;J. Isgaard;A. Lindahl;A. Dahlstrom;A. Skottner;O.G.P. Isaksson
  16. Gen. Comp. Endocrinol. v.100 no.3 Immunohistochemical localization of insulin-like growth factor I and II in the endocrien pancreas of birds,reptiles and amphiboia Renecke, M.;I. Broger;R. Burn;J. Zapf;C. Maake
  17. J. Biol. Chem. v.262 no.22 in vivo regulation of cycle AMP phosphodiesterase in Xenpous oocytes.stimulation by insuluin and insulin-like growth factor 1 Sadler,S.E.;J.L. Maller
  18. Development v.122 Expression and functional involvement of N- cadherin in embryonic limb chondrogenesis Oberlender,S.A.;R.S. Tuan
  19. Biol. Physiol. Pharmacol.Txicol. Endocrinnol. v.117 no.3 Hormonal control of the in vitro uptake of 「35s」sulfate by cartilage of Xenopus laevis tadoles Schneider, A.;W. Hanke;W.
  20. Korean J. Electron Microscopy v.27 no.2 Ultrastrural study of induced otic vesicle from isolated Xenopus presumptive ectoderm Yoon, C.S.;D.H. Kim;S.W. Cheng