Microsotructure Designed Porous Apatite Ceramics Prepared by Hydrothermal Method

  • Ioku, Koji (Department of Advanced Materials and Engineering, Faculty of Engineering) ;
  • Fukuhara, Michiko (Department of Advanced Materials and Engineering, Faculty of Engineering Yamaguchi University) ;
  • Fujimori, Hirotaka (Department of Advanced Materials and Engineering, Faculty of Engineering Yamaguchi University) ;
  • Goto, Seishi (Department of Advanced Materials and Engineering, Faculty of Engineering Yamaguchi University)
  • Published : 1999.06.01

Abstract

Microsotructure designed porous ceramics of calcium hydroxyapatite $(Ca_{10}(PO_4)_6(OH)_2)$ were prepared by hydrothermal method. The particle size, shape, and the micro-pore size of the porous hydroxyapatite ceramics could becontrolled. The hydroxyapatite was non-stoichiometric apatite with calcium deficient compositions (Ca/P ratio < 1.67). The composition of non-stoichiometric hydroxyapatite ceramics could be controlled from 1.50 to 1.63 in Ca/P ratio. The hydroxyapatite ceramics preparedc at $105^{\circ}C$ under the saturated vapor pressure for 20h were composed of rod-shaped crystals with about 10$\mu\textrm{m}$ in length with the mean aspect ratio of 40. The porous ceramics of calcium deficient hydroxyapatite had about 45% porosity with the inter-connecting pore structure. Porous hydroxyapatite ceramics prepared hydrothermally had the compressive strength of about 10 to 30 MPa. In addition, porous ceramics of $\beta$-tricalcium phosphate ($\beta-Ca_3(PO_4)_2$) were prepared from the calcium deficient hydroxyapatite.

Keywords

References

  1. Apatite(Proc. 1st Int. Sympo. Apatitite, Mishima, Japan) v.1 History of the Use of Hydroxyapatite as a Biomaterial S. F. Hulbert;H. Aoki(ed.);M. Akao(ed.);N. Nagai(ed.);T. Tsuji(ed.)
  2. Ishiyaku EuroAmerica Medical Applications of Hydroxyaaptite H. Aoki
  3. Phosphorus Research Bulletin v.4 Low Temperature Sintering of Hydroxyapatite by Hydrothermal Hot-Pressing K. Ioku;K. Yamamoto;K. Yanagisawa;N. Yamasaki
  4. Solvo-Thermal Reactions(Proc. 1st Int. Conf. Solvo-Thermal Reactions, Takamatsu, Japan) v.1 Apatite Ceramics Pared by Hydrothermal Hot-Pressing K. Ioku;K. Yamamoto;K. Yanagisawa;N.Yamasaki
  5. Phosphorus Research Bulletin v.4 Hardened Material of Calcium-Alumino-Silicate Glass and Calcium Phosphate by Hydrothermal Treatment S. Goto;M. Hirata;T. Obana;K. Ioku
  6. Solvo-Thermal Reactions(Proc. 1st Int. Conf. Solvo-Thermal Reactions, Takamatsu, Japan) v.1 Hydrothermal Hardening of Calicum-Alumino-Silicate Glass with Calcium Phosphate S. Goto;M. Hirata;T. Obana;K. Ioku
  7. J. Ceram. Soc. Japan, Int.(Edition) v.100 Preparation of Microstructure-Controlled Porous Hydroxyapatite-β-Tricalcium Phosphate Composites by Reaction Sintering K. Ioku;T. Murakami;Y. Ikuma;M. Yoshimura
  8. J. Ceram. Soc. Japan(Yogyo-Kyokai-Shi) v.84 no.4 The Hydration of a-Tricalcium Phospate H. Monma;T. Kanazawa
  9. J. Ceram. Soc. Japan(Seramikkusu Ronbunshi) v.98 no.3 Densification of Calcium-Deficient Hydroxyapatite by Hot Isostatic pressing S. R. Kim;K. Hirota;F. P. Okamura;Y. Hasegawa;S. J. Park
  10. J. Mater. Sci.: Materials in Medicine v.4 Determination of the Ca/P Ratio in Calcium-deficient Hydroxyapatit using X-ray Diffraction Analysis K. Ishikawa;P. Ducheyne;S. Radin
  11. Bioceramcis v.9 Reaction of Porous β-TCP with Different Microstructure in Vivo K. Ioku;S. Goto;H. Kurosawa;K. Shibuya;H. Yokozeki;T. Hayashi;T. Nakagawa;T. Kokubo(Ed.);T. Nakamura(Ed.);F. Miyaji(Ed.)
  12. J. Mater. Sci.: Materials in Medicine v.9 no.7 Influence of Surface Microstructure on the Reaction of the Active Ceramics in Vivo H. Yokozeki;T. Hayashi;T. Nakagawa;H. Kurosawa;K. Shibuya;K. Ioku