Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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effects of Safflower Seed(Carthamus timctorious L. Powder on Lipid Metabolism in High Fat and High Cholesterol-Fed Rats

홍화종실분말 식이가 고지방-고콜레스테롤섭취 흰쥐의 지질대사에 미치는 영향

  • 문광덕 (경북대학교 식품공학과) ;
  • 김준한 (경북대학교 식품공학과) ;
  • 전선민 (경북대학교 식품영양학과) ;
  • 박영애 (경북대학교 식품공학과) ;
  • 최명숙 (경북대학교 식품영양학과)
  • Published : 1999.06.01
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Abstract

A study was carried out to investigate the effects of safflower seed powder on the improvement of lipid metabolism in high fat and high cholesterol fed rats. Male Sprague Dawley rats of 10 weeks old, weighing 325$\pm$5g, were divided into two groups; the control group(C group, high fat(10% lard) and high cholesterol(1% cholesterol)) and safflower seed group(S group, 10% safflower seed powder), they were fed experimental diets for 6 weeks. Food intake, body weight gains and organ weight had little differences between the groups. Concentration of lipoprotein in serum was remarkably lower in S group than in C group. Serum cholesterol levels were significantly lower in S group(72.94$\pm$4.08 mg/dl) than in C group(89.41$\pm$4.19mg/dl). The level of serum HDL cholesterol was higher in S group than in C group. The level of serum LDL C was significantly lower in S group than in C group. The ratio of HDL cholesterol to total cholesterol were higher in the S group than in the C group, too. The value of atherogenic index(AI) was determined to be low in S group. The content of liver triglyceride and cholesterol in the S group was lower than that of C group. ACAT activities which involves in cholesterol esterification in liver, was not significantly different between two groups.

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