Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Iron Bioavailability in Iron-fortified Market Milk

철분강화 우유의 생이용성 평가

  • Published : 1999.06.01
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Abstract

To evaluate iron bioavailability in iron fortified milk, in vitro and in vivo method were used. Low molecular weight components(ILC) from milk was isolated and iron was added, then soluble iron from ILC iron complex was determined. Each iron sources and extrinsically labelled with FeCl3 was used for measuring absorption rate of iron from ILC radiolabelled iron complexes as radioiron absorption into the blood one hour after injection into ligated duodenal loops of iron deficient rats. Iron absorption rate was in the order of ferrous lactate(25.56%)$\geq$ferric citrate(24.71%)$\geq$ferrous sulfate(19.67%) when 100ppm iron was used. In separate experiments, iron fortified milks with each iron sources were gavaged into iron deficient rats. When 25ppm iron was added to milk, the order of iron absorption was ferrous sulfate(12.52%)>ferrous lactate(8.07%)>ferric citrate(6.52%) (p<0.05). When 100ppm iron was added to milk, absorption rate was decreased compared to the treatments with added 25ppm of iron. Absorption rate of ferrous sulfate(5.34%) from milk added 100ppm iron was highly lowered, but ferric citrate(6.45%) was not significantly changed. The absorption rate of ferrous lactate(5.82%) was 70% of 25ppm iron added milk.

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References

  1. Clin. Physiol. Biochem. v.7 Biochemistry of nonheme iron in man Bezkorovainy, A.
  2. Iron metabolism in man Bothwell, T. H.;Charlton, R. W.;Cook, J. D.;Finch, C. A.
  3. Clin. Physiol. Biochem. v.4 Iron metabolism Finch, C. A.;Hueber, H. A.
  4. J. Agr. Food Chem. v.18 Biological availability in animals of iron from common dietary sources Fritz, J. C.;Pla, G. W.;Roberts, T.;Boehme, J. W.;Hove, E. L.
  5. Ann. Rev. Nutr. v.1 Bioavailability of dietary factors which impact iron bioavailability Hallberg, L.
  6. J. Am. Diet. Assoc. v.88 Iron nutrition and absorption: dietary factors which impact iron bioavailability Monsen, E. R.
  7. Blut. v.55 Intestinal iron sbsorption and mucosal transferrin in rats subjected to hypoxia Ostrloh, K. R. S.;Simpson, R. J.;Snape, S.;Peters, T. J.
  8. Biological TraceElement Research v.19 What can in vitro methods tell us about mineral availability? Johnson, P. E.
  9. Am. J. Clin. Nutr. v.34 A comparison of in vivo and in ritro methods for determining availability of iron from meals Schricker, B. R.;Miller, D. D.;Rasmussen, R. R.;Van Campen, D.
  10. Blood v.33 Food iron absorption: A comparison of vegetable and animal food Layrisse, M.;Cook, J. D.;Martinez-Torres, C.;Finch, C. A.
  11. Am. J. Clin. Nutr. v.21 Effect of interaction of various foods on iron absorption Layrisse, M.;Martinez-Torres, C.;Roche, M.
  12. Food Tech. v.37 Physicochemical determinants of iron bioavailability Clydesdale, F. M.
  13. J. Food Sci. v.46 Effect of pH and heat treatment on the binding of calcium, magnesium, zinc, and iron to wheat bran and fractions of dietary fiber Camire, A. L.;Clydesdale, F. M.
  14. J. Nutr. v.115 Availability to rats of iron in ferric hydroxide polymers Berner, L. A.;Miller, D. D.;Van Carmpen, D.
  15. J. Food Sci. v.47 Effects of storage on the bioavailability and chemistry of iron powders in a heat-processed liquid milk-based product Clemens, R. A.
  16. J. Dairy Sci. v.54 Effects on flavor of fortifying milk with iron and absorption of the iron from intestinal tract of rats Demtt, B. J.
  17. J. Agric. Food Chem. v.27 Effects of supplemental iron and copper on lipid oxidation in milk Hegenauer, J.;Saltman, P.;Ludwig, D.;Ripley, L.;Bajo, P.
  18. J. Food Sci. v.51 Protective effect of milk on mineral precipitation by Na phytate Platt, S.;Nadeau, D. B.;Gifford, S. R.;Clydesdale, F. M.
  19. J. Food Sci. v.48 Iron-enriched bread: Interaction effect of protein quality and copper on iron bioavailability Ranhorta, G.;Gelroth, J.;Novak, F.;Bock, A.;Bohannon, F.
  20. Am. J. Clin. Nutr. v.62 Effect of milk and fermeted on iron absorption in ileostomy subjects Tiedehag, P.;Sandvberg, A.;Hallmans, G.;Wing, K.;Turk, M.;Holm, S.;Grahn, E.
  21. Anal. Biochem. v.10 Spectrometric determination of serum iron at the submicrogram level with a new reagent(Ferrozine) Carter, P.
  22. Am. J. Clin. Nutr. v.39 In vitro estimation of the effects of selected proteins on iron bioavailability Kane, A. P.;Miller, D. D.
  23. Meat effects on nonheme iron absorption. Ph. D. thesis Kim, Y.
  24. J. Food Sci. v.48 Effects of product formulation, processing, and meal composition of in vitro estimated iron availability from cereal-containing breakfast meals Carlson, B. L.;Miller, D. D.
  25. Am. J. Physiol. v.203 Active transport of iron by intestine: features of the two-step mechanisms Manis, J. G.;Schachter, D.
  26. Physiol. Rev. v.53 Iron absorption Forth, W.;Rummel, W.