Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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A Simulation Model for the protein Deposition of Pigs According to Amino Acid Composition of Feed Proteins

사료의 아미노산 조성에 따른 돼지의 단백질 축적을 나타내는 수치모델

  • 이옥희 (용인대학교 식품영양학과) ;
  • 김강성 (용인대학교 식품영양학과)
  • Published : 1999.02.01
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Abstract

This study was conducted to develop a simulation model for the growth dynamics of pigs and to describe quantitatively protein deposition depending on the amino acid composition of feed protein. In the model it is assumed that the essential processes that determine the utilization of feed protein in the whole body are protein synthesis, breakdown of protein, and oxidation of amino acid. Besides, it is also assumed that occurrence of protein deposition depends on genetic potential and amino acid composition of feed protein. The genetic potential for the protein deposition is the maximum capacity of protein synthesis, being dependent on the protein mass of the whole body. To describe the effect of amino acid composition of feed on the protein deposition, a factor, which consist of ten amino acid functions and lie between 0 and 1, is introduced. Accordingly a model was developed, which is described with 15 flux equations and 11 differential equations and is composed of two compartments. The model describes non linear structure of the protein utilization system of an organism, which is in non steady state. The objective function for the simulation was protein deposition(g/day) cal culated according to the empirical model, PAF(product of amino acid functions) of Menke. The mean of relative difference between the simulated protein deposition and PAF calculated values, lied in a range of 11.8%. The simulated protein synthesis and breakdown rates(g/day) in the whole body showed a parallel behavior in the course of growth.

Keywords

References

  1. Arch. Anat. Physiol. Abst. v.219 Uber die biologische Wertigkeit der stickstoffsubstanz in verschiedenen Mahrungsintteln Thomas, K.
  2. Poultry science symposium no. 19 Response to amino acids:Nutrient requirements of poultry and nutritional research Boorman, K. N.;Burgess, A. D.;Fisher, C.;Boorman, K. N.(eds.)
  3. Pretentin turnover in mammalian tissues and in the whole body Waterlow, J. C.;Garlic, P. J.;Millward, D. J.
  4. Wahl der Mahrungsprotein, Grundlagen und Diatetik Some aspects of in vivo human protein and amino modulation Young, V. R.;Fugawa, N.;Beir, D. M.;Matthews, D.
  5. The mathematical modiling of metabolic and endocrine systems-model formation, identification and validation Carson, E. R.;Cobelli, c.;Finkelstein, L.
  6. Protein metabolism and nutrition v.16 no.Ⅱ The product of amino acid functions(PAF) as a meaure of protein quality for pigs Menke, K. H.;Gruber, F.;Gaus, G.;Pion, R.;Arnal, M.;Bonin, D.(eds.)
  7. Poultry science symposium no. 19 The statistical approach to nutrient requirements:Nutrient, requirements of poultry and nutritional research Curnew, R. N.;Fisher, C.;Boorman, K. N.(eds.)
  8. J. Nutr. v.112 Modification of the saturation kidetics models to produce a more versatile protein quality assay Phillips, R. D.
  9. Clin. Sci. v.33 Lysine turnover in man meaured by intravenous infusion of L-[U-C]-lysine Waterlow, J. C.
  10. J. Clin, Invest. v.77 Lysine and protein metabolism in young women subdivision based on the model-use of multiple stavle labels Irving, C. S.;Thomas, M. R.;Malphus, E. W.;Marks, L.;Wong, W. W.;Bouton, t. W.;Klein, P. O.
  11. Substrate and energy metabolism in man Human protein requirements, the phusiological significance of changes in the role of whole body rrotein turnover Millward, D. J.;Garrow, J. S.;Halliday, D.(eds.)
  12. J. Biol. Chem. v.257 The role of amino acids in the regulation of protein synthesis in perfused rat liver. 1. Reduction in rates of synthesis resulting from amino acid deprivation and recovery during flow through perfusion Flaim, K. E.;Peavy, D. E.;Everwon, W. V.;Jefferson, L. S.
  13. The nutrient requirement of pigs Agricultural research council(ed.)
  14. Systemanalyse und Modelaufbau-Grun-dlagen der symulationstechnik v.1 Schmidt, B.
  15. Proc. Nutr. Soc. v.39 The use of a computer model in determining the nutrient requirement of pigs Whittemore, C. T.
  16. Ubers. Tierernahrg. v.12 Phydiological basis of the protein requirements of pig Wiesemuller, W.
  17. Fette Seifen Anstrichmittel v.80 Stoffwechselphysiologie der protein und Aminosaurin Erbersdobler, H.
  18. Tierernaehung und Futtermittelkunde Menke, K. H.;Huss, W.
  19. Arch. Tiernahrg. v.39 N-Stoffwechsel und seine Regelmechanismen Bergner, H.
  20. Arch. Tiernahrg. v.37 Effect of protein quality on energy requirements for maintenance in growing rats Aguilar, J. F.;Prieto, C.
  21. Milkporteins: nutritonal, clinical, functional and technical aspects The endocrine response to dietary protein:the anabolic drive on growth Millward, D. J.;Barth, C. A.;Schlimme, E.(eds.)
  22. 생물전산학 James, D. S.;박석순(역)
  23. Math-Naturwiss v.22 Die Dynamik des Aminosaurenstoffwechsels monogastrischer Tierarten unter verschiedenen. Wiss. Z. Un.v. Rostock Wiesmuller, W.
  24. Ubers. Tierernahrg. v.5 Der Proteinansatz beim Schwein und seine Beeinflussung durch exogene und endoge Faktoren Berschauer, F.
  25. J. Nutr. v.102 Efficiency of utilization of indispensable amino acids for growth by the rat Aguilar, T. S.;Harper, A. E.;Benevenga, N. J.
  26. Proc. Third EAAP symp. EAAP publ. 27 v.1 The effect of dietary energy and protein on protein turnover and nitrogen balance in growing pig:Protein metabolism and nutritions Reeds, P. J.;Fuller, M. F.;Cadenhead, A.;Lobly, G. E.
  27. Numerical initial value problem in ordinary differential equations Gear, C. W.
  28. Kor. J. Nutr. v.26 Simulation of the effect of protein quality at the different protein intake level on protein vetabolism Lie, O. H.
  29. Abschluss-Bericht aus dem SFB 142-A. Menke, K . H.
  30. Brit. J. Nutr. v.31 Dietary amino acids: effect of depletion and recovery on protein synthesis in vitro in rat skeletal muscle and liver Omstedt, P. T.;Von der Deckin, A.
  31. Brit. Poul. Sci. v.28 Influence of dietary protein intake on whole-body protein turnover in chicks Muramatsu, T. K.;Kita, A.;Tasaki, A.;Okumura, J.
  32. Brit. J. Nutr. v.46 Characterstics of skeletal muscle growth and protein turnover in a fast growing rat strain Bates, P. C.;Millward, D. J.
  33. Biochem. J. v.217 Protein turnover and growth in the whole body, liver and kidney of the rat from foetus to senility Goldspink, D. F.;Kelly, F. J.
  34. J. Nutr. v.115 Skeletal muscle protein turnover in young male pigs Mulvaney, D. R.;Merkel, R. A.;Bergen, W. G.
  35. Poul. Sci. v.66 Whole-body protein turnover in chicks fed control-histidine or methionine plus custine-free diet Kino, K.;Okumura, J. I.
  36. Ann. Nutr. Metabol. v.31 Response of muscle, liver and whole-body turnover totwo different source of protein in growing rats Martinez, J. A.;Goena, M.;Santidrian, S.;Lorrale, J.
  37. Am. J. Physiol. v.256 Effect of amino acid deprivation on intiation of protein synthesis in isolated rat hepatocytes Everson, W. V.;Flaim, K. E.;Susco, D. M.;Kimball, S. R.;Jefferson, L. S.
  38. Nitrogen metabolism in man Free amino acid pools and their regulation Waterlow, J. C.;Fern, F. B.;Waterlow, J. C.;Stephen, J. M. C.(eds.)
  39. J. Nutr. v.90 Arginine-lysine antagonism in the chick and its relationship to dietary cations O'Dell, B. L.;Savage, J. E.
  40. J. Nutr. v.105 Effects of amino acid imbalance and protein content of diet on food in take and preference of young, adult and diabetic rat Peng, Y.;Meliza, Vavich, M. C.;Kemmerer, A. R.
  41. Proc. 6th Cong. ESPEN Regulation of intracellular metabolism of amino acids: Nutrition in cancer and trauma sepsis Furst, P.;Boulzett, F.;Dionigi, P.(eds.)
  42. Brit. J. Nutr. v.32 The metabolism of 14Clabelled essential amino acids given by intragastric or intravenous infusion to rats in normal and protein free diets Neale, R. J.;Waterlow, J. C.
  43. Brit. J. Nutr. v.50 Amino acid oxidation by young pigs receiving diets with varying levels of sulphur amino acids Kim, K.;Bayley, H. S.
  44. Metab. v.37 Rate of whole-body protein synthesis in the rat as calculatedfrom fractional oxidation of leucine, valine or methionine Immura, K.;Walser, M.
  45. Advances in enzyme regulation v.10 Some aspects of the regulation of fuel supply in omnivorous animals Krebs, H. A.;Weber, G.(ed.)
  46. Absorption and utilization of amino acids v.1 Methionine, homocyst (e)ine, cyst(e)ine-metabolic interrelationships Smolin, L. A.;Benevenga, N. J.;Friedmann, M.(ed.)
  47. Brit. J. Nutr. v.36 The relative effects of low-protein-high carbohydate kiet on the free amino acid composition of liver and muscle Lunn, P. H.;Whitehead, R. G.;Baker, B. A.
  48. Proc. Nutr. Soc. v.42 Some recent developments in the study of amino acid metabilism Harper, A. E.
  49. Brit. J. Nutr. v.54 Efficiency of utilization of essential amino acids in growing rats at different levels of intake Heger, J.;Frydrych, Z.
  50. J. Nutr. v.114 The effect of amino acid excess on utilization by the rat of limiting amino acid-lysine and threonine at equalized food intake Cieslak, D. J.;Benevenga, N. T.
  51. Z. Tierphysiol. Tierernarg. Futtermittelkde. v.61 Ansatz und Verwertung von Aminosauren bei frueh abgesetzent Ferkeln nach qualitativ und quantiativ unterschiedlichen Proteinyufuhr. Kirchgessner, M. W.;Staudarer, W.;Steinhart, H. S.
  52. Am. J. Clin. Nutr. v.46 Kinetics of human amino acid metabolism; nutritional implications and some lessens Young, V. R.
  53. Am. J. Clin. Nutr. v.43 Lysine kinetics at graded lysine intake in young men Meredith, C. N.;Wen, z. W.;Bier, D. M.;Matthews, D. E.;Young, V. R.
  54. J. Nutr. v.107 Effect of histidine intake and hepatic histidase activity on the metabolism of histidine in vivo Kang-Lee, T. A.;Harper, A. E.