Antioxidative and Hepatoprotective Activity of Colured-Scented and Korean Native Rice Varieties Based on Different Layers

특수 유색미, 향류미 및 한국 재래종 벼 종자의 층위별 항산화 및 간보호 활성

  • 박희준 (상지대학교 생명자원과학대학) ;
  • 곽태순 (상지대학교 생명자원과학대학) ;
  • 정원태 (일양약품 중앙연구수) ;
  • 최종원 (경성대학교 약학대학)
  • Published : 1999.02.01

Abstract

Fifteen varieties of Oryza sativa mainly including those of Korean native rice were exactly cutted into three layers such as L1 layer(the outer part of 92% from rice center), L2 layer(the part of 81∼91% from the rice center) and L3 layer(the inner part of 80% from the rice center) We biologically evaluated the antioxidative effect on the every layer(L1, L2 and L3) of all the varieties, by observing malondialdehyde (MDA) produced by galactosamine in the mouse. L1 layer of some varieties showed significant antiox idative effect, while L2 and L3 layer didn't show the activity. It was also suggested that coloured rice(Suwon 425 and Sanggaehangbyeolna) showed stronger activity than other general rices, probably due to high contents of anthocyanins. Successively, we evaluated antihepatotoxic effect, based on the determination of serum ALT and AST activity. Some varieties of only L1 layer, except for L2 and L3 layer, significantly decreased the serum ALT and AST activity. This finding indicate that oral diet of some raw rice are able to protect hepatotoxicities. Among all the samples tested, L1 layer of Suwon 425 showed the strongest antihepatotoxic effect. From quantitative analysis on ferulic acid derivatives, it was found that the more it enters from the surface into the rice center, the more those secondary metabolites contents were highly reduced. These findings above suggested that Suwon 425 could be a promising candidate for the development of health rice food.

Keywords

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