Effects of Fermented Milk Feeding on Function and Suppression of Aluminum Accumulation in Kidney of Rat

젖산균 발효유 섭취가 흰쥐의 신장내 알루미늄 축적억제와 신장기능에 미치는 영향

  • 김중만 (원광대학교 생명자원과학대학) ;
  • 박성수 (송원전문대학 식품영양과) ;
  • 백승화 (충북도립옥천대학 식품공업과) ;
  • 정동현 (축산협동조합중앙회 한국양봉 인천공장) ;
  • 최용배 (원광대학교 생명자원과학대학) ;
  • 신용서 (원광대학교 생명자원과학대학) ;
  • 한성희 (원광대학교 생명자원과학대학) ;
  • 홍가형 (원광대학교 생명자원과학대학)
  • Published : 1999.02.01

Abstract

This study was performed to evaluate the effects of the supplementation of lactic acid bacterias (LAB; S. thermophilus, L. acidophilus) aluminum accumulation and function kidney in rats treated with 250 g/g aluminum sulfate for 4 weeks. Fifty male Sprague Dawley strains were divided into five groups according to the types of supplement. the control, S. thermophilus culture group(A), autoclaved S. thermophilus culture(B), L. acidophilus culture group(C) and autoclaved L. acidophilus(D). The weight gain was increased by supplementation of S. thermophilus culture(A), autoclaved S. thermophilus culture(B), L. acidophilus culture(C), autoclaved L. acidophilus culture(D), especially by supplementation of S. thermophilus cultured(A) as compared to control group. The amount of water intake was increased in control group as compared to the LAB supplemented group. The content of aluminum were decreased 19.57%, 31.25%, 37.10%, and 32.40% in kidney after supplementation of non autoclaved culture group (A,C), and autoclaved group(B,D) respectively, as compared to control group. Water balance, urine volume, and excretion of sodium and potassium decreased in LAB supplemented group and control group. Excretion of creatinine increased in control group and tendency to increased in LAB supplemented group. In conclusion, the effect of suppression of aluminum accumulation was more effective in sup plementation of S. thermophilus culture(A), and L. acidophilus culture(C) than autoclaved S. thermo philus culture(B), and L. acidophilus culture(D).

Keywords

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