High Level of Trans-Resveratrol, a Natural Anti-Cancer Agent, Found in Korean Noul Red Wine

  • KIM, KWANG-SEOK (Department of Microbiology, Kyungpook National University) ;
  • SA-YOUL GHIM (Department of Biology Education, Kyungpook National University) ;
  • YOUNG-BAE SEU (Department of Microbiology, Kyungpook National University) ;
  • BANG-HO SONG (Department of Biology Education, Kyungpook National University)
  • Published : 1999.10.01


Resveratrol (trans-3,5,4'-trihydroxystilbene), a phenolic substance present in both grapes and wines, has been reported to have certain pharmacological effects. Using an ethylacetate-phase extraction followed by a high performance liquid chromatographic analysis, the concentration of trans-resveratrol was measured in 9 red wines commercially available in Korea, including the Korean red wine (Noul). Noul red wine with a 1998 vintage had a trans-resveratrol concentration of 3.3 ㎎/l, which was rather higher than the concentrations found in other wines (0.19-2.45 ㎎/l) with the exception of the French wine, J. P. Chenet (3.39 ㎎/l). In addition, the grapes of Vitis labrusca cv. Sheridan cultivated in the Kyungsan area showed a trans-resveratrol content of 6.4 ㎎/㎏.


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