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Synthesis of Pyrrolo[2,3-c]acridines


초록

The synthesis of 6-amino-3-benzylpyrrolo[2,3-c]acridine (9) and its 8,9-dimethoxy derivative (10) from N-benzyl-4,5,6,7-tetrahydroindol-4-one and anthranilonitriles, via imine formation followed by cyclization and aromatisation, is described.

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참고문헌

  1. Adv. Heterocycl. Chem. v.70 Groundwater, P.W.;Munawar, M.A.
  2. J. Chem. Soc., Perkin Trans. I Groundwater, P.W.;Munawar, M.A.
  3. Bull. Soc. Chim. Fr. v.9-10 Takagi, K.;Kobayashi, N.;Ueda, T.
  4. J. Org. Chem. v.36 Remers, W.A.;Roth, R.H;Gibs, G.J.;Weiss, M.J.