The Korean Journal of Pesticide Science (농약과학회지)
- Volume 3 Issue 3
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- Pages.11-19
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- 1999
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- 1226-6183(pISSN)
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- 2287-2051(eISSN)
Structure-activity relationships on the selective herbicidal activity between rice plant and barnyard grass by the N-phenyl substituents in 2-(4-(6-chloro-2-benzoxazolyloxy)-phenoxy)-N-phenyl propionamide derivatives
2-(4-(6-chloro-2-benzoxazolyloxy) phenoxy)-N-phenyl propionamide 유도체 중 N-phenyl 치환체들에 의한 벼와 피의 선택적 제초활성에 미치는 구조-활성관계
- Sung, Nack-Do (Division of Applied Biology & Chemistry, Chung-Nam National University) ;
- Lee, Sang-Ho (Division of Applied Biology & Chemistry, Chung-Nam National University) ;
- Chang, Hae-Sung (Korea Research Institute of Chemical Technology) ;
- Kim, Dae-Whang (Korea Research Institute of Chemical Technology) ;
- Kim, Jin-Suk (Korea Research Institute of Chemical Technology)
- 성낙도 (충남대학교 응용생물화학부) ;
- 이상호 (충남대학교 응용생물화학부) ;
- 장해성 (한국화학연구소 신물질연구부) ;
- 김대황 (한국화학연구소 신물질연구부) ;
- 김진석 (한국화학연구소 스크리닝연구부)
- Published : 1999.12.30
Abstract
A some of synthesized 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenyl propionamide derivativesa substrates were found to selectivity significantly with both rice plant (Oryza sativa L.) and barnyard grass (Echinochloa crus-galli) for those her- bicidal activities with post emergence in up land. The selectivity of substrates against rice plant better than that of Fenoxaprop-ethyl. The structure activity relationship (SAR) n the selectivity of N-phenyl substituents were analyzed by the Free-Wilson and Hansch method. The SAR approach against barnyard grass is shown that the optimal (
Fenoxaprop-ethyl계 화합물의 amide 형태로 합성된 기질로써 일련의 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenylpropionamide 유도체들은 건답에서 발아 후 (post), 벼와 피 (Echinochloa crus-galli)에 대하여 Fenoxaprop-ethyl 보다 비교적 양호한 선택성을 나타내었으며 N-phenyl 치환체들의 선택성에 관한 구조-활성과의 관계 (SAR)를 Free-Wilson 방법과 Hansch 방법을 이용하여 정량적으로 검토하였다. 피의 제초활성에는 N-phenyl 고리상 meta-치환된 1 치환체들과 ortho, meta, para-치환된 3 치환체로서 methyl 및 methoxy 등의 치환체들이 비교적 높게 기여하였다. 또한 적정값 (
Keywords
- 2-(4-(6-chloro-2-benzoxazolyloxy) phenoxy)-N-phenylpropionamide;
- Herbicidal activity;
- Barnyard grass(Echinochloa crus-galli);
- Up land;
- Selectivity;
- QSAR. Hansch & Free-Wilson method