The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)
- Volume 12 Issue 1
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- Pages.1-17
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- 1999
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
Studies on the Inhibitory effect of anaphylactic reaction by Shinisan
辛夷散에 의한 아나필락시 反應의 抑制에 관한 硏究
- Published : 19990200
Abstract
Shinisan has been used for treatment of allergic disease in Oriental Medicine. However, its effect in experimental models remains unknown. The mast cell plays a pivotal role in initiating allergic response by secreting intracytoplasmic granular mediators such as histamine. The present report describes an inhibitory effect of Shinisan on mast cell-mediated immediate type allergic reactions. Topical application of compound 48/80 can induce an ear swelling response in normal (
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