Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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COMPARATIVE STUDY OF WOUND HEALING FOLLOWING PARTIAL GLOSSECTOMY OF RAT TONGUE USING CO2 LASER AND SCALPEL

$CO_2$ 레이저와 일반 수술도를 이용한 백서의 부분적설 절제술 후의 창상치유에 관한 비교연구

  • Jang, Jae-Pil (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University) ;
  • Kim, Kyung-Wook (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University) ;
  • Lee, Jae-Hoon (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University) ;
  • Kim, Chang-Jin (Dept. of Pathology, College of Medicine, Soonchunhyang University)
  • 장재필 (단국대학교 치과대학 구강악안면외과학교실) ;
  • 김경욱 (단국대학교 치과대학 구강악안면외과학교실) ;
  • 이재훈 (단국대학교 치과대학 구강악안면외과학교실) ;
  • 김창진 (순천향대학교 의과대학 병리학교실)
  • Published : 2000.10.30
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Abstract

Object This study is focused on the comparison between $CO_2$ laser and scalpel by examining the overal process of wound healing after partial glossectomy of rats so that the result from the research could be easily applied to actual clinical environment. Method and Material In this research, 2mm defect was formed on both lateral borders of the tongue of rats by using $CO_2$ laser and scalpel respectively. 4rats were sacrified each time on the 1st, 2nd, 4th, 7th, 14th and 21th day according to a general method. After fabricating $5{\mu}m$ paraffin specimen, H&E staining and MT staining were performed. Results Compared to scalpel, wound healing by $CO_2$ laser leads to a earlier initiation of vascular proliferation and re-epithelization. Therefore, some influence is exerted on the early stage of wound healing. However, the two methods seem to undergo the similar healing process.

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